Are α-Blockers Beneficial for Outpatient Management of Uncomplicated Ureteric Stones?

The initial search strategy identified 443 unique studies; screening against inclusion or exclusion criteria yielded 55 randomized controlled trials comparing α-blocker medical expulsive therapy for passage of uncomplicated ureteric stones less than 10 mm versus either a placebo (14 studies) or expectant management (41 studies) control. Tamsulosin was the primary α-blocker used (40 of 55 studies), at various dosages (0.2 to 0.4 mg) and for various durations (7 to 30 days); however, the results did not differ among α-blockers.

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