In Regard to Renz et al

To the Editor: We would like to comment on the recently published retrospective review by Renz et al on adjuvant radiation therapy (RT) for excised keloids.1 Most patients in this series received 20 Gy in 5 fractions at 1 institution versus 12 Gy in 3 fractions or 16 Gy in 4 fractions at a second institution. Three other schedules were also used (18 Gy in 3 fractions, 15 Gy in 3 fractions, and 10 Gy in 2 fractions) for small numbers of patients. The authors concluded that there was a dose-response relationship for local control, with recurrence rates of 1.6% for the 20 Gy in 5 fractions and higher biologically equivalent dose2 group versus 9.6% for the lower biologically equivalent dose2 group.

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