Αρχειοθήκη ιστολογίου

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Κυριακή 19 Ιανουαρίου 2020

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

MDPI
 International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 659: Night Shift Work—A Risk Factor for Breast CancerIJERPH, Vol. 17, Pages 659: Night Shift Work—A Risk Factor for Breast Cancer International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020659 Authors: Marta Szkiela Ewa Kusideł Teresa Makowiec-Dąbrowska Dorota Kaleta Shift work is considered a risk factor for some health problems. This study aimed to determine whether night shift...
Medicine by Alexandros G. Sfakianakis
08:56
MDPI
 NanomaterialsNanomaterials, Vol. 10, Pages 164: Surface-Enhanced Raman Spectroscopy on Hybrid Graphene/Gold Substrates near the Percolation ThresholdNanomaterials, Vol. 10, Pages 164: Surface-Enhanced Raman Spectroscopy on Hybrid Graphene/Gold Substrates near the Percolation Threshold Nanomaterials doi: 10.3390/nano10010164 Authors: Dmitry E. Tatarkin Dmitry I. Yakubovsky Georgy A. Ermolaev Yury V. Stebunov Artem A. Voronov Aleksey V. Arsenin Valentyn S. Volkov Sergey M. Novikov Graphene is a promising...
Medicine by Alexandros G. Sfakianakis
08:55
MDPI
 International Journal of Molecular SciencesIJMS, Vol. 21, Pages 634: Genome-Wide Identification and Characterization of the NAC Transcription Factor Family in Musa Acuminata and Expression Analysis during Fruit RipeningIJMS, Vol. 21, Pages 634: Genome-Wide Identification and Characterization of the NAC Transcription Factor Family in Musa Acuminata and Expression Analysis during Fruit Ripening International Journal of Molecular Sciences doi: 10.3390/ijms21020634 Authors: Bin Li Ruiyi Fan Qiaosong...
Medicine by Alexandros G. Sfakianakis
08:52
MDPI
 MedicinaMedicina, Vol. 56, Pages 42: Accuracy of the qSOFA Score and RED Sign in Predicting Critical Care Requirements in Patients with Suspected Infection in the Emergency Department: A Retrospective Observational StudyMedicina, Vol. 56, Pages 42: Accuracy of the qSOFA Score and RED Sign in Predicting Critical Care Requirements in Patients with Suspected Infection in the Emergency Department: A Retrospective Observational Study Medicina doi: 10.3390/medicina56010042 Authors: Jong Eun Park Sung...
Medicine by Alexandros G. Sfakianakis
08:51
MDPI
 DiseasesDiseases, Vol. 8, Pages 3: Acknowledgement to Reviewers of Diseases in 2019Diseases, Vol. 8, Pages 3: Acknowledgement to Reviewers of Diseases in 2019 Diseases doi: 10.3390/diseases8010003 Authors: Diseases Editorial Office Diseases Editorial Office The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal's rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]DiseasesSun...
Medicine by Alexandros G. Sfakianakis
08:47
MDPI
 AntibioticsAntibiotics, Vol. 9, Pages 38: Prevalence of Antibiotics Prescription and Assessment of Prescribed Daily Dose in Outpatients from Mexico CityAntibiotics, Vol. 9, Pages 38: Prevalence of Antibiotics Prescription and Assessment of Prescribed Daily Dose in Outpatients from Mexico City Antibiotics doi: 10.3390/antibiotics9010038 Authors: Ramiro Sánchez-Huesca Abel Lerma Rebeca M.E Guzmán-Saldaña Claudia Lerma Pharmacoepidemiological research about antibiotics is supported by the World Health...
Medicine by Alexandros G. Sfakianakis
08:45
Postoperative oscillatory brain activity as an add-on prognostic marker in diffuse glioma
Postoperative oscillatory brain activity as an add-on prognostic marker in diffuse glioma: AbstractIntroductionProgression-free survival (PFS) in glioma patients varies widely, even when stratifying for known predictors (i.e. age, molecular tumor subtype, presence of epilepsy, tumor grade and Karnofsky performance status). Neuronal activity has been shown to accelerate tumor growth in an animal model, suggesting that brain activity may be valuable as a PFS predictor. We investigated whether postoperative...
Medicine by Alexandros G. Sfakianakis
08:42
Efficacy of sequential radiation and chemotherapy in treating glioblastoma with poor performance status
Efficacy of sequential radiation and chemotherapy in treating glioblastoma with poor performance status: AbstractIntroductionWhile the current standard of care after maximal safe resection for glioblastoma (GBM) is concomitant radiation and chemotherapy, the ideal therapy for patients with poor performance status remains in question due to concerns about treatment tolerance. We sought to evaluate an alternative regimen, sequential radiation and chemotherapy, to assess its efficacy as a treatment...
Medicine by Alexandros G. Sfakianakis
08:42
Imaging glioma biology: spatial comparison of amino acid PET, amide proton transfer, and perfusion-weighted MRI in newly diagnosed gliomas
Imaging glioma biology: spatial comparison of amino acid PET, amide proton transfer, and perfusion-weighted MRI in newly diagnosed gliomas: AbstractPurposeImaging glioma biology holds great promise to unravel the complex nature of these tumors. Besides well-established imaging techniques such O-(2-[18F]fluoroethyl)-l-tyrosine (FET)-PET and dynamic susceptibility contrast (DSC) perfusion imaging, amide proton transfer–weighted (APTw) imaging has emerged as a promising novel MR technique. In this study,...
Medicine by Alexandros G. Sfakianakis
08:42
Quantifying the effects of absorbed dose from radioembolisation on healthy liver function with [ 99m Tc]TcMebrofenin
Quantifying the effects of absorbed dose from radioembolisation on healthy liver function with [ 99m Tc]TcMebrofenin: AbstractPurposeTo quantify the effects of absorbed radiation dose on healthy liver parenchyma following radioembolisation (RE) using [99mTc]TcMebrofenin to analyse both global and regional liver function.MethodsPatients having RE to treat hepatic disease underwent a [99mTc]TcMebrofenin hepatobilliary scintigraphy (HBS) study at both baseline and 8 weeks following treatment. Changes...
Medicine by Alexandros G. Sfakianakis
08:41
Perioperative EOX in D2 Gastrectomy
Real-World Long-Term Outcomes with Perioperative EOX in D2 Gastrectomy: a Meaningful Look While We Switch to FLOT-4: AbstractIntroductionData regarding long-term survival and prognosis in loco-regionally advanced, non-metastatic gastric cancers (GC) using perioperative chemotherapy and D2 lymphadenectomies from India is scarce.Materials and MethodsThe study is a retrospective evaluation of locally advanced gastric cancers who received epirubicin-oxaliplatin-capecitabine (EOX) as perioperative therapy...
Medicine by Alexandros G. Sfakianakis
08:41
The Degradation of Phenanthrene, Pyrene, and Fluoranthene and Its Conversion into Medium-Chain-Length Polyhydroxyalkanoate by Novel Polycyclic Aromatic Hydrocarbon-Degrading Bacteria
The Degradation of Phenanthrene, Pyrene, and Fluoranthene and Its Conversion into Medium-Chain-Length Polyhydroxyalkanoate by Novel Polycyclic Aromatic Hydrocarbon-Degrading Bacteria: AbstractScreening of high-efficient polycyclic aromatic hydrocarbon (PAH)-degrading bacteria is important due to environmental contamination by PAHs. In this study, sediment contaminated with phenanthrene (Phe), pyrene (Pyr), and fluoranthene (Fluo) was used as a source of bacteria. The ability of these isolated bacteria...
Medicine by Alexandros G. Sfakianakis
08:41
Association between household food insecurity and mortality
Association between household food insecurity and mortality in Canada: a population-based retrospective cohort study [Research]: BACKGROUND:Food insecurity affects 1 in 8 households in Canada, with serious health consequences. We investigated the association between household food insecurity and all-cause and cause-specific mortality.METHODS:We assessed the food insecurity status of Canadian adults using the Canadian Community Health Survey 2005–2017 and identified premature deaths among the survey...
Medicine by Alexandros G. Sfakianakis
08:41
The Role of the Oral Healthcare Team in Identification of Type 2 Diabetes Mellitus: A Systematic Review
The Role of the Oral Healthcare Team in Identification of Type 2 Diabetes Mellitus: A Systematic Review: AbstractPurpose of ReviewType 2 diabetes (T2DM) presents a growing global health and economic burden. Dental settings have been employed to identify individuals who may be at high risk of diabetes, who exhibit non-diabetic hyperglycaemia (NDH – also termed "prediabetes") and who already unknowingly have the condition, through the use of targeted risk-assessments. This review aims to synthesize...
Medicine by Alexandros G. Sfakianakis
08:40
The Oral Microbiome and Lung Diseases
The Oral Microbiome and Lung Diseases: AbstractPurpose of ReviewThe understanding of the human microbiome, especially of the oral cavity, has expanded exponentially since the advent of 16 rRNA PCR gene sequencing. Since the respiratory tract starts from the oral cavity and ends in the lung, study of the relationship between the oral microbiota and the lungs will allow us to understand the changes in lung disease compared with healthy state.Recent FindingsThe oral and lung microbiota were found to...
Medicine by Alexandros G. Sfakianakis
08:40
Could Vitamin D Influence Risk for Periodontal Disease—to "D" or Not to "D"?
Could Vitamin D Influence Risk for Periodontal Disease—to "D" or Not to "D"?: AbstractPurpose of ReviewThe purpose of this review is to discuss the literature on associations between vitamin D and periodontal disease, including its strengths and weaknesses. Future direction for continued work in this area is provided.Recent FindingsResearch in cross-sectional cohorts, surveys, and case-control studies provide support for a role of vitamin D in periodontal disease, especially using clinical indicators...
Medicine by Alexandros G. Sfakianakis
08:40
Molecular characterization of multidrug-resistant Gram-negative pathogens
Molecular characterization of multidrug-resistant Gram-negative pathogens in three tertiary hospitals in Cairo, Egypt: AbstractHigh rates of antimicrobial resistance (AMR) among Gram-negative pathogens (GNP) have been reported in Egypt. Antimicrobial surveillance and identifying the genetic basis of AMR provide important information to optimize patient care. In this study, we aimed to identify the beta-lactam resistance phenotypes and genotypes of multidrug-resistant (MDR) non-repetitive GNP from...
Medicine by Alexandros G. Sfakianakis
08:39
Causes of fever in pregnant women with acute undifferentiated fever
Causes of fever in pregnant women with acute undifferentiated fever: a prospective multicentric study: AbstractThe etiologies of undifferentiated fever in pregnant women have not been studied thoroughly. Because of its non-specific presentation but severe prognosis, listeriosis is often suspected in this setting, but in most cases not confirmed. We studied the causes of undifferentiated fever in pregnant women who received preemptive listeriosis treatment. We conducted from November 1, 2011, to June...
Medicine by Alexandros G. Sfakianakis
08:39
Evaluation of EUCAST rapid antimicrobial susceptibility testing (RAST) directly from blood culture bottles
Evaluation of EUCAST rapid antimicrobial susceptibility testing (RAST) directly from blood culture bottles: AbstractThis study was performed to evaluate EUCAST blood culture (BC) rapid antimicrobial susceptibility testing (RAST) for Gram-negative organisms. Clinical BCs positive with Gram-negative-bacilli between April 23, 2019 and June 21, 2019, and 41 spiked isolates were tested by RAST against ceftazidime, piperacillin-tazobactam, meropenem, ciprofloxacin, gentamicin, and amikacin and compared...
Medicine by Alexandros G. Sfakianakis
08:39
Evaluation of serological diagnostic tests of human brucellosis
Evaluation of serological diagnostic tests of human brucellosis for prevention and control in Mexico: AbstractBrucellosis is a zoonosis mainly present in developing countries. The WHO reports 500,000 new cases every year. From 2012 to 2016, 13,677 cases were reported in Mexico, with 2.00 to 2.64 rate per 100,000 inhabitants. To analyze the diagnostic algorithm of brucellosis in Mexico, we compared the commercial laboratory tests ELISA, Brucellacapt®, and lateral flow test (LFT) in a study of 473...
Medicine by Alexandros G. Sfakianakis
08:39
piRNAs: biogenesis and their potential roles in cancer
piRNAs: biogenesis and their potential roles in cancer: AbstractWith the length of about 26–31 nt, PIWI-interacting RNA (piRNA) is a small non-coding RNA (ncRNA) that interacts with PIWI proteins to form the piRNA silencing complex (piRISC). PIWI is a subfamily of Argonaute, and piRNA must bind to PIWI to exert its regulatory role. Current studies indicated that piRNA and PIWI are significantly abnormally expressed in gastric, breast, kidney, colon, and lung cancers, and are involved in the initiation,...
Medicine by Alexandros G. Sfakianakis
08:38
Notch signaling patterns head horn shape in the bull-headed dung beetle Onthophagus taurus
Notch signaling patterns head horn shape in the bull-headed dung beetle Onthophagus taurus: AbstractSize and shape constitute fundamental aspects in the description of morphology. Yet while the developmental-genetic underpinnings of trait size, in particular with regard to scaling relationships, are increasingly well understood, those of shape remain largely elusive. Here we investigate the potential function of the Notch signaling pathway in instructing the shape of beetle horns, a highly diversified...
Medicine by Alexandros G. Sfakianakis
08:38
Impact of Tai Chi Yuttari-exercise on arteriosclerosis and physical function in older people.
Impact of Tai Chi Yuttari-exercise on arteriosclerosis and physical function in older people.: Related ArticlesImpact of Tai Chi Yuttari-exercise on arteriosclerosis and physical function in older people.Arch Gerontol Geriatr. 2020 Jan 10;87:104011Authors: Mori K, Nomura T, Akezaki Y, Yamamoto R, Iwakura HAbstract OBJECTIVES: This non-randomized controlled study investigated the impact of practicing Tai Chi Yuttari-exercise for 1 year on arteriosclerosis status and physical functioning of...
Medicine by Alexandros G. Sfakianakis
08:37
Importance of Distal Sealing During Endovascular Aneurysm Repair Using Aneurysmal Common Iliac Artery as Landing Zone.
Importance of Distal Sealing During Endovascular Aneurysm Repair Using Aneurysmal Common Iliac Artery as Landing Zone.: Related ArticlesImportance of Distal Sealing During Endovascular Aneurysm Repair Using Aneurysmal Common Iliac Artery as Landing Zone.Ann Vasc Surg. 2020 Jan 14;:Authors: Shintani T, Mitsuoka H, Hasegawa Y, Hayashi M, Natsume K, Ookura K, Sato Y, Obara HAbstract BACKGROUND: Although the use of aneurysmal CIA as the landing zone during EVAR remains an essential procedure,...
Medicine by Alexandros G. Sfakianakis
08:37
Laser ablation of posterior nasal nerves for rhinitis.
Laser ablation of posterior nasal nerves for rhinitis.: Related ArticlesLaser ablation of posterior nasal nerves for rhinitis.Am J Otolaryngol. 2020 Jan 09;:102396Authors: Krespi YP, Wilson KA, Kizhner VAbstract BACKGROUND: Posterior nasal nerve (PNN) surgery, Radiofrequency (RF), and cryoablation have been described as alternative treatments for allergic and vasomotor rhinitis. We hypothesize that endoscopic (diode) laser ablation (ELA) is effective and less invasive than previously described...
Medicine by Alexandros G. Sfakianakis
08:36
Clinical frailty independently predicts early mortality after ischaemic stroke.
Clinical frailty independently predicts early mortality after ischaemic stroke.: Related ArticlesClinical frailty independently predicts early mortality after ischaemic stroke.Age Ageing. 2020 Jan 17;:Authors: Evans NR, Wall J, To B, Wallis SJ, Romero-Ortuno R, Warburton EAAbstract BACKGROUND: Clinical frailty is an important syndrome for clinical care and research, independently predicting mortality and rates of institutionalisation in a range of medical conditions. However, there has been...
Medicine by Alexandros G. Sfakianakis
08:36
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.: Related ArticlesAlda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.Aesthetic Plast Surg. 2020 Jan 17;:Authors: Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi FAbstract BACKGROUND: The cutaneous wound healing process mainly comprises re-epithelialization,...
Medicine by Alexandros G. Sfakianakis
08:36
Hyaluronic Acid Gel Injections in the Subcutis
Spreading Pattern and Tissue Response to Hyaluronic Acid Gel Injections in the Subcutis: Ultrasound Videos, Ultrasound Measurements, and Histology.: Related ArticlesSpreading Pattern and Tissue Response to Hyaluronic Acid Gel Injections in the Subcutis: Ultrasound Videos, Ultrasound Measurements, and Histology.Aesthet Surg J. 2020 Jan 17;:Authors: Vandeputte J, Leemans G, Dhaene K, Forsyth R, Vanslembrouck J, Hatem F, Micheels PAbstract BACKGROUND: Despite the popularity of hyaluronic acid...
Medicine by Alexandros G. Sfakianakis
08:36
Randomised oral stimulation and exclusive breastfeeding duration in healthy premature infants.
Randomised oral stimulation and exclusive breastfeeding duration in healthy premature infants.: Related ArticlesRandomised oral stimulation and exclusive breastfeeding duration in healthy premature infants.Acta Paediatr. 2020 Jan 18;:Authors: Skaaning D, Carlsen E, Brødsgaard A, Kyhnaeb A, Pedersen M, Ravn S, Pryds O, Kronborg HAbstract AIM: Although exclusive breastfeeding is recommended for all newborn in the first six months of life, only 13% of Danish premature infants complies with this....
Medicine by Alexandros G. Sfakianakis
08:35
Midfacial Clefting.
Finding the Unicorn, a New Mouse Model of Midfacial Clefting.: Related ArticlesFinding the Unicorn, a New Mouse Model of Midfacial Clefting.Genes (Basel). 2020 Jan 11;11(1):Authors: Lantz B, White C, Liu X, Wan Y, Gabriel G, Lo CWY, Szabo-Rogers HLAbstract Human midfacial clefting is a rare subset of orofacial clefting and in severe cases, the cleft separates the nostrils splitting the nose into two independent structures. To begin to understand the morphological and genetic causes of midfacial...
Medicine by Alexandros G. Sfakianakis
08:35
Perception and Acoustic Studies of Vowel Intelligibility in Dysphonic Speech.
Perception and Acoustic Studies of Vowel Intelligibility in Dysphonic Speech.: Related ArticlesPerception and Acoustic Studies of Vowel Intelligibility in Dysphonic Speech.J Voice. 2020 Jan 15;:Authors: Ishikawa K, Nudelman C, Park S, Ketring CAbstract PURPOSE: This study aimed to (1) examine the effect of dysphonia and background noise on the identifiability of vowels, and (2) evaluate the relationship between the degree of vowel intelligibility and vowel-related acoustic measurements. ...
Medicine by Alexandros G. Sfakianakis
08:34
Vaccines and immunology.
Panel 8: Vaccines and immunology.: Related ArticlesPanel 8: Vaccines and immunology.Int J Pediatr Otorhinolaryngol. 2019 Dec 18;:109839Authors: Alderson MR, Murphy T, Pelton SI, Novotny LA, Hammitt LL, Kurabi A, Li JD, Thornton RB, Kirkham LSAbstract OBJECTIVE: To review and highlight significant advances made towards vaccine development and understanding of the immunology of otitis media (OM) since the 19th International Symposium on Recent Advances in Otitis Media (ISOM) in 2015, as well...
Medicine by Alexandros G. Sfakianakis
08:34
Oral and maxillofacial cancer in pediatric patients
Oral and maxillofacial cancer in pediatric patients: 30 years experience from a Brazilian reference center.: Related ArticlesOral and maxillofacial cancer in pediatric patients: 30 years experience from a Brazilian reference center.Int J Pediatr Otorhinolaryngol. 2020 Jan 10;131:109879Authors: Arboleda LPA, Hoffmann IL, Cardinalli IA, Gallagher KPD, Santos-Silva AR, Mendonça RMHAbstract OBJECTIVE: The aim of this study is to determine the relative frequency, demographic distribution and clinicopathological...
Medicine by Alexandros G. Sfakianakis
08:34
Efficacy of melatonin for auditory brainstem response testing in children: A systematic review.
Efficacy of melatonin for auditory brainstem response testing in children: A systematic review.: Related ArticlesEfficacy of melatonin for auditory brainstem response testing in children: A systematic review.Int J Pediatr Otorhinolaryngol. 2020 Jan 03;131:109861Authors: Behrman DB, Bishop JL, Godsell J, Shirley B, Storey S, Carroll WW, Prosser JDAbstract OBJECTIVE: To examine the literature on pre-treatment with melatonin for successful completion of Auditory Brainstem Response (ABR) testing...
Medicine by Alexandros G. Sfakianakis
08:34
Female caregivers talk more to 18-56-months-old children with and without hearing impairment than male caregivers measured with LENA™ - A cross-sectional pilot study.
Female caregivers talk more to 18-56-months-old children with and without hearing impairment than male caregivers measured with LENA™ - A cross-sectional pilot study.: Related ArticlesFemale caregivers talk more to 18-56-months-old children with and without hearing impairment than male caregivers measured with LENA™ - A cross-sectional pilot study.Int J Pediatr Otorhinolaryngol. 2019 Nov 30;130:109809Authors: Kristensen NM, Sundby CF, Hauge MN, Löfkvist UAbstract The objective of the current...
Medicine by Alexandros G. Sfakianakis
08:33
Does delayed initiation of adjuvant chemotherapy following the curative resection affect the survival outcome of gastric cancer patients: A systematic review and meta-analysis.
Does delayed initiation of adjuvant chemotherapy following the curative resection affect the survival outcome of gastric cancer patients: A systematic review and meta-analysis.: Related ArticlesDoes delayed initiation of adjuvant chemotherapy following the curative resection affect the survival outcome of gastric cancer patients: A systematic review and meta-analysis.Eur J Surg Oncol. 2020 Jan 08;:Authors: Lu H, Zhao B, Zhang J, Huang R, Wang Z, Xu H, Huang BAbstract BACKGROUND: Adjuvant...
Medicine by Alexandros G. Sfakianakis
08:33
The role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.
The role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.: Related ArticlesThe role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.Eur J Surg Oncol. 2020 Jan 09;:Authors: Nixon IJ, Shah JP, Zafereo M, Simo RS, Hay ID, Suárez C, Zbären P, Rinaldo A, Sanabria A, Silver C, Mäkitie A, Vander Poorten V, Kowalski LP, Shaha AR, Randolph GW, Ferlito AAbstract...
Medicine by Alexandros G. Sfakianakis
08:33
Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.
Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.: Related ArticlesElevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.Cancer Med. 2020 Jan 16;:Authors: Suzuki K, Nishiwaki K, Gunji T, Katori M, Masuoka H, Yano SAbstract Lenalidomide is an immunomodulatory drug that is administered commonly in patients with relapsed or refractory...
Medicine by Alexandros G. Sfakianakis
08:32
Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.
Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.: Related ArticlesElevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide.Cancer Med. 2020 Jan 16;:Authors: Suzuki K, Nishiwaki K, Gunji T, Katori M, Masuoka H, Yano SAbstract Lenalidomide is an immunomodulatory drug that is administered commonly in patients with relapsed or refractory...
Medicine by Alexandros G. Sfakianakis
08:31
Novel cancer therapies for advanced cutaneous melanoma: The added value of radiomics in the decision making process-A systematic review.
Novel cancer therapies for advanced cutaneous melanoma: The added value of radiomics in the decision making process-A systematic review.: Related ArticlesNovel cancer therapies for advanced cutaneous melanoma: The added value of radiomics in the decision making process-A systematic review.Cancer Med. 2020 Jan 17;:Authors: Guerrisi A, Loi E, Ungania S, Russillo M, Bruzzaniti V, Elia F, Desiderio F, Marconi R, Solivetti FM, Strigari LAbstract Advanced malignant melanoma represents a public...
Medicine by Alexandros G. Sfakianakis
08:31
Long non-coding RNA ARAP1-AS1 promotes tumorigenesis and metastasis through facilitating proto-oncogene c-Myc translation via dissociating PSF/PTB dimer in cervical cancer.
Long non-coding RNA ARAP1-AS1 promotes tumorigenesis and metastasis through facilitating proto-oncogene c-Myc translation via dissociating PSF/PTB dimer in cervical cancer.: Related ArticlesLong non-coding RNA ARAP1-AS1 promotes tumorigenesis and metastasis through facilitating proto-oncogene c-Myc translation via dissociating PSF/PTB dimer in cervical cancer.Cancer Med. 2020 Jan 17;:Authors: Zhang Y, Wu D, Wang DAbstract Long non-coding RNA (lncRNA) is emerging as a pivotal regulator in...
Medicine by Alexandros G. Sfakianakis
08:31
Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway.
Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway.: Related ArticlesEffects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway.Cancer Med. 2020 Jan 17;:Authors: Zhang YF, Li CS, Zhou Y, Lu XHAbstract BACKGROUND: In the present study, we aim to investigate the potential role of propofol in the tumor progression of colon cancer. METHODS: Human colon cancer...
Medicine by Alexandros G. Sfakianakis
08:31
Phase 1 Fractional Dose-Escalation Study of Equipotent Stereotactic Radiation Therapy Regimens for Early-Stage Glottic Larynx Cancer.
Phase 1 Fractional Dose-Escalation Study of Equipotent Stereotactic Radiation Therapy Regimens for Early-Stage Glottic Larynx Cancer.: Related ArticlesPhase 1 Fractional Dose-Escalation Study of Equipotent Stereotactic Radiation Therapy Regimens for Early-Stage Glottic Larynx Cancer.Int J Radiat Oncol Biol Phys. 2019 09 01;105(1):110-118Authors: Sher DJ, Timmerman RD, Nedzi L, Ding C, Pham NL, Zhao B, Sumer BDAbstract PURPOSE: Early-stage glottic larynx squamous cell carcinoma (GLC) is a...
Medicine by Alexandros G. Sfakianakis
08:30
Cutaneous plasmacytosis and multinucleate cell angiohistiocytoma-like lesion in a patient with hepatitis B: A fortuitous triad?
Cutaneous plasmacytosis and multinucleate cell angiohistiocytoma-like lesion in a patient with hepatitis B: A fortuitous triad?: Related ArticlesCutaneous plasmacytosis and multinucleate cell angiohistiocytoma-like lesion in a patient with hepatitis B: A fortuitous triad?J Cutan Pathol. 2019 Sep;46(9):678-683Authors: Roy SF, Ghazawi FM, Tran D, Bouffard DAbstract A 28-year-old woman of Chinese descent, with congenital chronic hepatitis B presented with a 7-year history of erythematous-brown...
Medicine by Alexandros G. Sfakianakis
08:30
Pituitary Adenoma Concomitant with Chiari I Malformation: Case Report and Literature Review.
Pituitary Adenoma Concomitant with Chiari I Malformation: Case Report and Literature Review.: Related ArticlesPituitary Adenoma Concomitant with Chiari I Malformation: Case Report and Literature Review.World Neurosurg. 2019 Sep;129:45-48Authors: Villalonga JF, Pilonieta M, Revuelta Barbero JM, Carrau RL, Prevedello DMAbstract BACKGROUND: Pituitary adenomas (PA) are usually benign neoplasms. Chiari I malformation (CIM) is an uncommon finding. Isolated cases associating functional PA and CIM...
Medicine by Alexandros G. Sfakianakis
08:30
Thyroid neoplasm evaluation.
A pilot study examining Toronto-area family physician perspectives on thyroid neoplasm evaluation.: Related ArticlesA pilot study examining Toronto-area family physician perspectives on thyroid neoplasm evaluation.J Otolaryngol Head Neck Surg. 2019 May 30;48(1):24Authors: Kundra A, Goldstein DP, Wintemute K, Ghai S, Tsang RW, Gupta K, Mutasingwa DR, Weissberger J, Huszti E, Brown P, Jiang H, Sawka AMAbstract OBJECTIVE: The incidence of thyroid cancer (TC) is known to be very high in the Greater...
Medicine by Alexandros G. Sfakianakis
08:30
Superficial Femoral Artery Interposition Graft for Repair of a Ruptured Mycotic Common Carotid Artery Pseudoaneurysm: Case Report and Review of the Literature.
Superficial Femoral Artery Interposition Graft for Repair of a Ruptured Mycotic Common Carotid Artery Pseudoaneurysm: Case Report and Review of the Literature.: Related ArticlesSuperficial Femoral Artery Interposition Graft for Repair of a Ruptured Mycotic Common Carotid Artery Pseudoaneurysm: Case Report and Review of the Literature.World Neurosurg. 2019 Sep;129:130-132Authors: Baranoski JF, Wanebo JE, Heiland KE, Zabramski JMAbstract BACKGROUND: Indications for reconstruction of the common...
Medicine by Alexandros G. Sfakianakis
08:30
Meta-analysis of routine calcium/vitamin D3 supplementation versus serum calcium level-based strategy to prevent postoperative hypocalcaemia after thyroidectomy.
Meta-analysis of routine calcium/vitamin D3 supplementation versus serum calcium level-based strategy to prevent postoperative hypocalcaemia after thyroidectomy.: Related ArticlesMeta-analysis of routine calcium/vitamin D3 supplementation versus serum calcium level-based strategy to prevent postoperative hypocalcaemia after thyroidectomy.Br J Surg. 2019 08;106(9):1126-1137Authors: Sanabria A, Rojas A, Arevalo JAbstract BACKGROUND: The aim was to assess the effectiveness of routine administration...
Medicine by Alexandros G. Sfakianakis
08:29
Sclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis.
Sclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis.: Related ArticlesSclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis.Neurointervention. 2020 Jan 16;:Authors: De Maria L, De Sanctis P, Balakrishnan K, Tollefson M, Brinjikji WAbstract We performed a systematic review and meta-analysis of studies performing sclerotherapy for treatment of venous malformations (VMs) of the face, head and neck. It is our hope...
Medicine by Alexandros G. Sfakianakis
08:24
Alternative Applications of Trans-Oral Robotic Surgery (TORS): A Systematic Review.
Alternative Applications of Trans-Oral Robotic Surgery (TORS): A Systematic Review.: Related ArticlesAlternative Applications of Trans-Oral Robotic Surgery (TORS): A Systematic Review.J Clin Med. 2020 Jan 11;9(1):Authors: Cammaroto G, Stringa LM, Zhang H, Capaccio P, Galletti F, Galletti B, Meccariello G, Iannella G, Pelucchi S, Baghat A, Vicini CAbstract BACKGROUND: The role of robotic surgery in the field of oncology has been widely described, in particular for the tumours of the oropharynx...
Medicine by Alexandros G. Sfakianakis
08:24
The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma.
The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma.: Related ArticlesThe Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma.Int J Mol Sci. 2020 Jan 11;21(2):Authors: Boschert V, Klenk N, Abt A, Janaki Raman S, Fischer M, Brands RC, Seher A, Linz C, Müller-Richter UDA, Bischler T, Hartmann SAbstract Head and neck squamous cell carcinoma (HNSCC) is known to overexpress...
Medicine by Alexandros G. Sfakianakis
08:24
Impaired Glycolysis Promotes AlcoholExposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling.
Impaired Glycolysis Promotes AlcoholExposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling.: Related ArticlesImpaired Glycolysis Promotes AlcoholExposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling.Int J Mol Sci. 2020 Jan 11;21(2):Authors: Kang H, Choi SJ, Park KH, Lee CK, Moon JSAbstract Glucose metabolism is an important metabolic pathway in the auditory system. Chronic alcohol exposure can cause metabolic dysfunction in auditory cells during...
Medicine by Alexandros G. Sfakianakis
08:24
B cells and tertiary lymphoid structures promote immunotherapy response.
B cells and tertiary lymphoid structures promote immunotherapy response.: Related ArticlesB cells and tertiary lymphoid structures promote immunotherapy response.Nature. 2020 Jan 15;:Authors: Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben...
Medicine by Alexandros G. Sfakianakis
08:23
Diagnostic challenges in malignant tumors of nasal cavity and paranasal sinuses.
Diagnostic challenges in malignant tumors of nasal cavity and paranasal sinuses.: Related ArticlesDiagnostic challenges in malignant tumors of nasal cavity and paranasal sinuses.J Oral Maxillofac Pathol. 2019 Sep-Dec;23(3):378-382Authors: Devi CP, Devi KM, Kumar P, Amrutha Sindhu RVAbstract Introduction: Malignant tumors of sinonasal tract are extremely rare and comprise 3% of all head and neck malignant tumors. They constitute 0.2% of all invasive carcinomas. Sinonasal space is a small anatomical...
Medicine by Alexandros G. Sfakianakis
08:23
Labial hydatid cyst - A rare entity.
Labial hydatid cyst - A rare entity.: Related ArticlesLabial hydatid cyst - A rare entity.J Oral Maxillofac Pathol. 2019 Sep-Dec;23(3):418-421Authors: Banerjee A, Elangovan E, Mitra KS, Saha AAbstract Hydatid cyst is a parasitic infestation by tapeworm Echinococcus. This endemic disease is prevalent in the Middle East and Southeast Asian populations. This zoonotic disease is mainly transmitted by cattle and dogs. Few studies have been reported in the head-and-neck region. There are very few...
Medicine by Alexandros G. Sfakianakis
08:23
Meta-analysis on risk factors of squamous cell carcinoma of the tongue in young adults.
Meta-analysis on risk factors of squamous cell carcinoma of the tongue in young adults.: Related ArticlesMeta-analysis on risk factors of squamous cell carcinoma of the tongue in young adults.J Oral Maxillofac Pathol. 2019 Sep-Dec;23(3):450-457Authors: Mohideen K, Krithika C, Jeddy N, Bharathi R, Thayumanavan B, Sankari SLAbstract Tongue squamous cell carcinoma (TSCC) generally affects the older age group exposed to tobacco for an extended period. However, recent research points out that...
Medicine by Alexandros G. Sfakianakis
08:23
Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition.
Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition.: Related ArticlesInhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition.J Cancer. 2020;11(3):533-541Authors: Yun M, Choi AJ, Woo SR, Noh JK, Sung JY, Lee JW, Eun YGAbstract Objective: Human carbonyl reductase 1 (CBR1) plays key roles...
Medicine by Alexandros G. Sfakianakis
08:23
In silico analysis of the prognostic value of FAS mRNA in malignancies.
In silico analysis of the prognostic value of FAS mRNA in malignancies.: Related ArticlesIn silico analysis of the prognostic value of FAS mRNA in malignancies.J Cancer. 2020;11(3):542-550Authors: Chen Z, Wu J, Xu H, Yu X, Wang KAbstract Background: FAS is a classical death receptor involved in the FAS/FAS ligand (FASL) apoptosis pathway and plays a role in anti-tumor activity. Some studies have recently reported that FAS can serve as an oncogene that promotes tumor proliferation and maintains...
Medicine by Alexandros G. Sfakianakis
08:23
Diabetes and its Potential Impact on Head and Neck Oncogenesis.
Diabetes and its Potential Impact on Head and Neck Oncogenesis.: Related ArticlesDiabetes and its Potential Impact on Head and Neck Oncogenesis.J Cancer. 2020;11(3):583-591Authors: Wang X, Wang H, Zhang T, Cai L, Dai E, He JAbstract In recent years, the incidence of diabetes mellitus and cancer has increased sharply; indeed, these have become the two most important diseases threatening health and survival. Head and neck (HN) tumors are the sixth most common malignancies in humans. Numerous...
Medicine by Alexandros G. Sfakianakis
08:22
A Completely Unique Branching Pattern of the Facial Artery.
A Completely Unique Branching Pattern of the Facial Artery.: Related ArticlesA Completely Unique Branching Pattern of the Facial Artery.Plast Reconstr Surg Glob Open. 2019 Jul;7(7):e2305Authors: Nakamura K, Umezawa H, Yokoshima K, Nakamizo M, Ogawa RAbstract This case report describes a recent case where a patient with hypopharyngeal cancer underwent resection and reconstruction with a free jejunum flap and the surgeons found a rare variation in the branching pattern of the common carotid...
Medicine by Alexandros G. Sfakianakis
08:22
Patient-reported Aesthetic Satisfaction following Facial Skin Cancer Surgery Using the FACE-Q Skin Cancer Module.
Patient-reported Aesthetic Satisfaction following Facial Skin Cancer Surgery Using the FACE-Q Skin Cancer Module.: Related ArticlesPatient-reported Aesthetic Satisfaction following Facial Skin Cancer Surgery Using the FACE-Q Skin Cancer Module.Plast Reconstr Surg Glob Open. 2019 Sep;7(9):e2423Authors: Vaidya TS, Mori S, Khoshab N, Dusza SW, Bander T, Matros E, Rossi AM, Nehal KS, Lee EHAbstract Over 5 million basal and squamous cell skin cancers are diagnosed each year. Seventy to 80% of...
Medicine by Alexandros G. Sfakianakis
08:22
Effective Continuous Positive Airway Pressure Changes Related to Sleep Stage and Body Position in Obstructive Sleep Apnea during Upward and Downward Titration: An Experimental Study.
Effective Continuous Positive Airway Pressure Changes Related to Sleep Stage and Body Position in Obstructive Sleep Apnea during Upward and Downward Titration: An Experimental Study.: Related ArticlesEffective Continuous Positive Airway Pressure Changes Related to Sleep Stage and Body Position in Obstructive Sleep Apnea during Upward and Downward Titration: An Experimental Study.J Clin Neurol. 2020 Jan;16(1):90-95Authors: Lee EM, Lee TH, Park OL, Nam JGAbstract BACKGROUND AND PURPOSE: The...
Medicine by Alexandros G. Sfakianakis
08:22
Draf IIB with superior septectomy: finding the "middle ground".
Draf IIB with superior septectomy: finding the "middle ground".: Related ArticlesDraf IIB with superior septectomy: finding the "middle ground".Int Forum Allergy Rhinol. 2019 03;9(3):281-285Authors: Bhalla V, Sykes KJ, Villwock JA, Beahm DD, McClurg SW, Chiu AGAbstract BACKGROUND: Previous studies have demonstrated a high failure rate of endoscopic sinus surgery (ESS) with Draf IIa in patients with diffuse polyposis, asthma, and aspirin-exacerbated respiratory disease. A high percentage...
Medicine by Alexandros G. Sfakianakis
08:22
Double-blinded randomized controlled trial to evaluate a multimedia surgical care tour in improving patient satisfaction and knowledge after functional endoscopic sinus surgery.
Double-blinded randomized controlled trial to evaluate a multimedia surgical care tour in improving patient satisfaction and knowledge after functional endoscopic sinus surgery.: Related ArticlesDouble-blinded randomized controlled trial to evaluate a multimedia surgical care tour in improving patient satisfaction and knowledge after functional endoscopic sinus surgery.Int Forum Allergy Rhinol. 2019 03;9(3):286-291Authors: Ma Y, Zeiger J, McKee S, Yang A, Schaberg M, Del-Signore A, Govindaraj S,...
Medicine by Alexandros G. Sfakianakis
08:21
A Novel Tool for Nasal Polyp Investigation: An Ex vivo Organ Culture System.
A Novel Tool for Nasal Polyp Investigation: An Ex vivo Organ Culture System.: Related ArticlesA Novel Tool for Nasal Polyp Investigation: An Ex vivo Organ Culture System.Isr Med Assoc J. 2020 Jan;22(1):48-52Authors: Ilan O, Tal Y, Hershko AY, Shamriz O, Bohbot E, Tayeb S, Regev D, Panet A, Eliashar RAbstract BACKGROUND: Nasal polyps are three-dimensional structures arising from the mucosa of the upper airway. Due to their complexity, the reliability of single-layer cell cultures and animal...
Medicine by Alexandros G. Sfakianakis
08:21
Characterizing Brain Network Topology in Cervical Dystonia Patients and Unaffected Relatives via Graph Theory.
Characterizing Brain Network Topology in Cervical Dystonia Patients and Unaffected Relatives via Graph Theory.: Related ArticlesCharacterizing Brain Network Topology in Cervical Dystonia Patients and Unaffected Relatives via Graph Theory.Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:1694-1697Authors: Narasimham S, Sundarajan V, McGovern E, Quinlivan B, Killian O, O'Riordan S, Hutchinson M, Reilly RBAbstract Cervical Dystonia (CD) is a neurological movement disorder characterized by intermittent...
Medicine by Alexandros G. Sfakianakis
08:20
Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS.
Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS.: Related ArticlesStem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS.Cells. 2020 Jan 14;9(1):Authors: Schürmann M, Greiner JFW, Volland-Thurn V, Oppel F, Kaltschmidt C, Sudhoff H, Kaltschmidt BAbstract Cholesteatoma is a severe non-cancerous lesion of the middle ear characterized by massive inflammation, tissue destruction, and an abnormal growth of keratinized...
Medicine by Alexandros G. Sfakianakis
08:20
Dual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study.
Dual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study.: Related ArticlesDual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study.BMC Med Imaging. 2020 Jan 16;20(1):5Authors: Lv Y, Zhou J, Lv X, Tian L, He H, Liu Z, Wu Y, Han L, Sun M, Yang Y, Guo C, Li C, Zhang R, Xie C, Chen Y, Chen ZAbstract BACKGROUND: Differentiating...
Medicine by Alexandros G. Sfakianakis
08:20
Resident Education in Laryngeal Stroboscopy: Part II-Evaluation of a Multimedia Training Module.
Resident Education in Laryngeal Stroboscopy: Part II-Evaluation of a Multimedia Training Module.: Related ArticlesResident Education in Laryngeal Stroboscopy: Part II-Evaluation of a Multimedia Training Module.J Voice. 2020 Jan 13;:Authors: Jones JW, Baumanis MM, Perryman M, Sykes KJ, Villwock MR, Cabrera-Muffly C, Dowdall J, David Garnett J, Kraft SAbstract OBJECTIVE: To evaluate the efficacy of a web-based training module for teaching interpretation of laryngeal stroboscopy in a cohort...
Medicine by Alexandros G. Sfakianakis
08:20
Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet.
Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet.: Related ArticlesHearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet.Biochem Biophys Res Commun. 2020 Jan 13;:Authors: Kim YY, Chao JR, Kim C, Kim B, Thi-Thanh Nguyen P, Jung H, Chang J, Lee JH, Suh JGAbstract Age-related hearing loss (ARHL) is a neurodegenerative disease associated with an aged population....
Medicine by Alexandros G. Sfakianakis
08:20
Facial nerve and chorda tympani schwannomas: Case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment.
Facial nerve and chorda tympani schwannomas: Case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment.: Related ArticlesFacial nerve and chorda tympani schwannomas: Case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment.Auris Nasus Larynx. 2020 Jan 13;:Authors: Furukawa T, Fabbris...
Medicine by Alexandros G. Sfakianakis
08:19
Prevention of peridural adhesions in spinal surgery: Assessing safety and efficacy of Chitogel with Deferiprone in a sheep model.
Prevention of peridural adhesions in spinal surgery: Assessing safety and efficacy of Chitogel with Deferiprone in a sheep model.: Related ArticlesPrevention of peridural adhesions in spinal surgery: Assessing safety and efficacy of Chitogel with Deferiprone in a sheep model.J Clin Neurosci. 2020 Jan 13;:Authors: Vediappan RS, Mascarenhas A, Nguyen-Hoang A, Anne Fong S, Jukes A, Richter K, Bassiouni A, Patel S, Chryssidis S, Otto S, Moratti S, James Psaltis A, Vreugde S, Wormald PJAbstract ...
Medicine by Alexandros G. Sfakianakis
08:19
High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence.
High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence.: Related ArticlesHigh CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence.J Clin Pathol. 2020 Jan 16;:Authors: Klein Nulent TJW, van Es RJJ, Valstar MH, Smeele LE, Smit LA, Klein Gunnewiek R, Zuithoff NPA, de Keizer B, de Bree R, Willems SAbstract AIM: Treatment options for head and neck...
Medicine by Alexandros G. Sfakianakis
08:18
Carotid intimal sarcoma causing stroke and intracranial metastasis via tumor embolization.
Carotid intimal sarcoma causing stroke and intracranial metastasis via tumor embolization.: Related ArticlesCarotid intimal sarcoma causing stroke and intracranial metastasis via tumor embolization.Neurology. 2020 Jan 16;:Authors: Agarwal S, Derman A, Raz E, Hoda ST, Arcot K, Yaghi S, Sanger M, Kim S, Galetta SAbstract OBJECTIVE: To present the clinical, radiologic, and pathologic findings of a patient with carotid intimal sarcoma. METHODS: Detailed medical interview, neurologic examination,...
Medicine by Alexandros G. Sfakianakis
08:18
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.: Related ArticlesMelanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.Nat Commun. 2020 Jan 16;11(1):333Authors: Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJAbstract Cutaneous malignant melanoma is an...
Medicine by Alexandros G. Sfakianakis
08:18
Three-Dimensional Printing of the Nasal Cavities for Clinical Experiments.
Three-Dimensional Printing of the Nasal Cavities for Clinical Experiments.: Related ArticlesThree-Dimensional Printing of the Nasal Cavities for Clinical Experiments.Sci Rep. 2020 Jan 16;10(1):502Authors: Valtonen O, Ormiskangas J, Kivekäs I, Rantanen V, Dean M, Poe D, Järnstedt J, Lekkala J, Saarenrinne P, Rautiainen MAbstract 3D printing has produced many beneficial applications for surgery. The technique´s applicability in replicating nasal cavity anatomy for clinical use has not been...
Medicine by Alexandros G. Sfakianakis
08:17
Does Intravenous Contrast Improve the Diagnostic Yield of Fluorodeoxyglucose Positron-emission Tomography/Computed Tomography in Patients with Head-and-neck Malignancy.
Does Intravenous Contrast Improve the Diagnostic Yield of Fluorodeoxyglucose Positron-emission Tomography/Computed Tomography in Patients with Head-and-neck Malignancy.: Related ArticlesDoes Intravenous Contrast Improve the Diagnostic Yield of Fluorodeoxyglucose Positron-emission Tomography/Computed Tomography in Patients with Head-and-neck Malignancy.Indian J Nucl Med. 2020 Jan-Mar;35(1):13-16Authors: Barai S, Ora M, Gambhir S, Singh AAbstract Introduction: In the present time, iodinated...
Medicine by Alexandros G. Sfakianakis
08:17
Effect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Sellar and Parasellar Tumor Resection: A Multicenter Prospective Randomized Controlled Trial.
Effect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Sellar and Parasellar Tumor Resection: A Multicenter Prospective Randomized Controlled Trial.: Related ArticlesEffect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Sellar and Parasellar Tumor Resection: A Multicenter Prospective Randomized Controlled Trial.Neurosurgery. 2020 Jan 17;:Authors: Yan CH, Rathor A, Krook K, Ma Y, Rotella MR, Dodd RL, Hwang PH, Nayak JV, Oyesiku...
Medicine by Alexandros G. Sfakianakis
08:17
The repertoire of tumor-infiltrating lymphocytes within the microenvironment of oral squamous cell carcinoma reveals immune dysfunction.
The repertoire of tumor-infiltrating lymphocytes within the microenvironment of oral squamous cell carcinoma reveals immune dysfunction.: Related ArticlesThe repertoire of tumor-infiltrating lymphocytes within the microenvironment of oral squamous cell carcinoma reveals immune dysfunction.Cancer Immunol Immunother. 2020 Jan 16;:Authors: Quan H, Shan Z, Liu Z, Liu S, Yang L, Fang X, Li K, Wang B, Deng Z, Hu Y, Yao Z, Huang J, Yu J, Xia K, Tang Z, Fang LAbstract BACKGROUND: The role of tumor-infiltrating...
Medicine by Alexandros G. Sfakianakis
08:15
Modified facelift approach for posterior segmental mandibulectomy: a blend of oncology and cosmesis.
Modified facelift approach for posterior segmental mandibulectomy: a blend of oncology and cosmesis.: Related ArticlesModified facelift approach for posterior segmental mandibulectomy: a blend of oncology and cosmesis.Eur Arch Otorhinolaryngol. 2020 Jan 16;:Authors: Rao V, Subash A, Sinha P, Prasad R, Majumdar K, Puranik PAbstract BACKGROUND: The approach to the mandible for segmental resection in malignant pathologies entails a lip-split, angle-split or visor flap incision with extension...
Medicine by Alexandros G. Sfakianakis
08:15
Multimodal Therapy for Sinonasal Malignancies: Updates and Review of Current Treatment.
Multimodal Therapy for Sinonasal Malignancies: Updates and Review of Current Treatment.: Related ArticlesMultimodal Therapy for Sinonasal Malignancies: Updates and Review of Current Treatment.Curr Treat Options Oncol. 2020 Jan 16;21(1):4Authors: Mody MD, Saba NFAbstract OPINION STATEMENT: Sinonasal malignancies pose a significant challenge in management due to their low incidence, biologic diversity, and significant symptom burden. Even though surgery remains the primary therapeutic modality,...
Medicine by Alexandros G. Sfakianakis
08:15
Classifying Neck Lymph Nodes of Head and Neck Squamous Cell Carcinoma in MRI Images with Radiomic Features.
Classifying Neck Lymph Nodes of Head and Neck Squamous Cell Carcinoma in MRI Images with Radiomic Features.: Related ArticlesClassifying Neck Lymph Nodes of Head and Neck Squamous Cell Carcinoma in MRI Images with Radiomic Features.J Digit Imaging. 2020 Jan 16;:Authors: Ho TY, Chao CH, Chin SC, Ng SH, Kang CJ, Tsang NMAbstract The aim of this study is to develop a computer-aided diagnosis method to help classify medical images of neck lymph nodes in head and neck cancer patients. According...
Medicine by Alexandros G. Sfakianakis
08:15
A 12-channel flexible receiver coil for accelerated tongue imaging.
A 12-channel flexible receiver coil for accelerated tongue imaging.: Related ArticlesA 12-channel flexible receiver coil for accelerated tongue imaging.MAGMA. 2020 Jan 16;:Authors: Voskuilen L, de Heer P, van der Molen L, Balm AJM, van der Heijden F, Strijkers GJ, Smeele LE, Nederveen AJAbstract OBJECTIVE: MRI of the tongue requires acceleration to minimise motion artefacts and to facilitate real-time imaging of swallowing. To accelerate tongue MRI, we designed a dedicated flexible receiver...
Medicine by Alexandros G. Sfakianakis
08:15
Soft Tissue Special Issue: Giant Cell-Rich Lesions of the Head and Neck Region.
Soft Tissue Special Issue: Giant Cell-Rich Lesions of the Head and Neck Region.: Related ArticlesSoft Tissue Special Issue: Giant Cell-Rich Lesions of the Head and Neck Region.Head Neck Pathol. 2020 Jan 16;:Authors: Lee JC, Huang HYAbstract Giant cell-rich lesions represent a heterogeneous group of tumors and non-neoplastic lesions, usually arising in bone, which harbor varying number of reactive osteoclastic-type multinucleate giant cells as a common feature. Among these entities, some are...
Medicine by Alexandros G. Sfakianakis
08:15
Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck.
Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck.: Related ArticlesSoft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck.Head Neck Pathol. 2020 Jan 16;:Authors: Tran NA, Guenette JP, Jagannathan JAbstract Bone and soft tissue sarcomas of the head and neck are a heterogenous group of tumors with overlapping features. Distinguishing between the various subtypes is challenging but necessary for appropriate diagnosis and...
Medicine by Alexandros G. Sfakianakis
08:15
Soft Tissue Special Issue: Adamantinoma-Like Ewing Sarcoma of the Head and Neck: A Practical Review of a Challenging Emerging Entity.
Soft Tissue Special Issue: Adamantinoma-Like Ewing Sarcoma of the Head and Neck: A Practical Review of a Challenging Emerging Entity.: Related ArticlesSoft Tissue Special Issue: Adamantinoma-Like Ewing Sarcoma of the Head and Neck: A Practical Review of a Challenging Emerging Entity.Head Neck Pathol. 2020 Jan 16;:Authors: Rooper LM, Bishop JAAbstract Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma that is defined by complex epithelial differentiation, including expression...
Medicine by Alexandros G. Sfakianakis
08:14
Soft Tissue Special Issue: Myoepithelial Neoplasms of Soft Tissue: An Updated Review with Emphasis on Diagnostic Considerations in the Head and Neck.
Soft Tissue Special Issue: Myoepithelial Neoplasms of Soft Tissue: An Updated Review with Emphasis on Diagnostic Considerations in the Head and Neck.: Related ArticlesSoft Tissue Special Issue: Myoepithelial Neoplasms of Soft Tissue: An Updated Review with Emphasis on Diagnostic Considerations in the Head and Neck.Head Neck Pathol. 2020 Jan 16;:Authors: Jo VYAbstract Primary myoepithelial neoplasms of soft tissue have been shown to be related to their salivary gland counterparts, with which...
Medicine by Alexandros G. Sfakianakis
08:14
Soft Tissue Special Issue: Skeletal Muscle Tumors: A Clinicopathological Review.
Soft Tissue Special Issue: Skeletal Muscle Tumors: A Clinicopathological Review.: Related ArticlesSoft Tissue Special Issue: Skeletal Muscle Tumors: A Clinicopathological Review.Head Neck Pathol. 2020 Jan 16;:Authors: Kohashi K, Kinoshita I, Oda YAbstract Skeletal muscle tumors are classified into rhabdomyoma and embryonal, alveolar, spindle cell/sclerosing and pleomorphic rhabdomyosarcoma according to WHO classifications of tumors. These tumors arise mostly in the head and neck and, in childhood,...
Medicine by Alexandros G. Sfakianakis
08:14
Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.
Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.: Related ArticlesSoft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.Head Neck Pathol. 2020 Jan 16;:Authors: Baranov E, Hornick JLAbstract Fibroblastic and myofibroblastic neoplasms of the head and neck encompass a group of rare tumor types with often overlapping clinicopathologic features that range in biologic potential from benign to overtly malignant. Even...
Medicine by Alexandros G. Sfakianakis
08:14
Soft Tissue Special Issue: Selected Topics in the Pathology of Adipocytic Tumors.
Soft Tissue Special Issue: Selected Topics in the Pathology of Adipocytic Tumors.: Related ArticlesSoft Tissue Special Issue: Selected Topics in the Pathology of Adipocytic Tumors.Head Neck Pathol. 2020 Jan 16;:Authors: Shon W, Billings SDAbstract Our understanding of adipocytic tumors classification and diagnosis continues to evolve. We present a brief review and updated summary of selected adipocytic tumors involving the head and neck region. For the practicing pathologist, knowledge of...
Medicine by Alexandros G. Sfakianakis
08:14
Soft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck.
Soft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck.: Related ArticlesSoft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck.Head Neck Pathol. 2020 Jan 16;:Authors: Flucke U, Karanian M, Broek RWT, Thway KAbstract Perivascular and vascular neoplasms of the head and neck are a rare group of tumors comprising a spectrum of clinical/biologic and histological features. They are frequently diagnostically challenging, due to their morphologic...
Medicine by Alexandros G. Sfakianakis
08:14
The Outcome of Early Ablative Fractional Laser Treatment for Thyroidectomy Scars.
The Outcome of Early Ablative Fractional Laser Treatment for Thyroidectomy Scars.: Related ArticlesThe Outcome of Early Ablative Fractional Laser Treatment for Thyroidectomy Scars.Lasers Surg Med. 2020 Jan 16;:Authors: You HJ, Choi YS, Hwang NH, Kim DW, Oh KH, Kwon SYAbstract BACKGROUND AND OBJECTIVES: Ablative fractional laser (AFL) systems are commonly used to treat various scars, and recent research has indicated that early treatment with AFL may have a preventive effect on scars. This...
Medicine by Alexandros G. Sfakianakis
08:13
Surgical treatment of epiglottis collapse in obstructive sleep apnoea syndrome: epiglottis stiffening operation.
Surgical treatment of epiglottis collapse in obstructive sleep apnoea syndrome: epiglottis stiffening operation.: Related ArticlesSurgical treatment of epiglottis collapse in obstructive sleep apnoea syndrome: epiglottis stiffening operation.Acta Otorhinolaryngol Ital. 2019 Dec;39(6):404-408Authors: Salamanca F, Leone F, Bianchi A, Bellotto RGS, Costantini F, Salvatori PPMID: 31950932 [PubMed - in process]
Medicine by Alexandros G. Sfakianakis
08:13
Streamlining care in cystic fibrosis: survey of otolaryngologist, pulmonologist, and patient experiences.
Streamlining care in cystic fibrosis: survey of otolaryngologist, pulmonologist, and patient experiences.: Related ArticlesStreamlining care in cystic fibrosis: survey of otolaryngologist, pulmonologist, and patient experiences.Int Forum Allergy Rhinol. 2020 Jan 17;:Authors: Farzal Z, Dean KM, Sreenath SB, Hodge SE, Thorp BD, Ebert CS, Zanation AM, Senior BA, Kimple AJAbstract BACKGROUND: Care coordination for cystic fibrosis (CF) is essential. The objectives of this study were to: (1) compare...
Medicine by Alexandros G. Sfakianakis
08:13
The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.
The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.: Related ArticlesThe Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.Phys Ther. 2020 Jan 17;:Authors: Parrington L, Jehu DA, Fino PC, Stuart S, Wilhelm J, Pettigrew N, Murchison CF, El-Gohary M, VanDerwalker J, Pearson S, Hullar T, Chesnutt JC, Peterka...
Medicine by Alexandros G. Sfakianakis
08:13
Decreased DNA Damage Repair in Response to Targeted Therapies Facilitates the Emergence of Drug-Resistant Clones.
This Is Our Cells Under Pressure: Decreased DNA Damage Repair in Response to Targeted Therapies Facilitates the Emergence of Drug-Resistant Clones.: Related ArticlesThis Is Our Cells Under Pressure: Decreased DNA Damage Repair in Response to Targeted Therapies Facilitates the Emergence of Drug-Resistant Clones.Cancer Cell. 2020 Jan 13;37(1):5-7Authors: Gay CM, Parseghian CM, Byers LAAbstract In a recent issue of Science, Russo et al. observe that colorectal cancer cells, when exposed to the...
Medicine by Alexandros G. Sfakianakis
08:12
Casticin elicits inflammasome-induced pyroptosis through activating PKR/JNK/NF-κB signal in 5-8F cells.
Casticin elicits inflammasome-induced pyroptosis through activating PKR/JNK/NF-κB signal in 5-8F cells.: Related ArticlesCasticin elicits inflammasome-induced pyroptosis through activating PKR/JNK/NF-κB signal in 5-8F cells.Biomed Pharmacother. 2020 Jan 14;123:109576Authors: Jiang C, Shi R, Chen B, Yan X, Tang GAbstract Casticin is one of the effective ingredients of fructus viticis. Most studies have shown that casticin has a strong anti-proliferation activity against various tumor cells....
Medicine by Alexandros G. Sfakianakis
08:12
A Cross-Sectional Study of Caregiver Perceptions of Congenital Cytomegalovirus Infection: Knowledge and Attitudes about Screening.
A Cross-Sectional Study of Caregiver Perceptions of Congenital Cytomegalovirus Infection: Knowledge and Attitudes about Screening.: Related ArticlesA Cross-Sectional Study of Caregiver Perceptions of Congenital Cytomegalovirus Infection: Knowledge and Attitudes about Screening.J Pediatr. 2020 Jan 14;:Authors: Diener ML, Shi K, Park AHAbstract OBJECTIVES: To understand caregiver knowledge of and attitudes toward congenital cytomegalovirus (cCMV) testing in Utah. STUDY DESIGN: We surveyed...
Medicine by Alexandros G. Sfakianakis
08:12
Amateur Music Theatre Singers' Perceptions of their Current Singing Voice Function.
Amateur Music Theatre Singers' Perceptions of their Current Singing Voice Function.: Related ArticlesAmateur Music Theatre Singers' Perceptions of their Current Singing Voice Function.J Voice. 2020 Jan 14;:Authors: Vella B, Brown L, Phyland DAbstract PURPOSE: The primary aim of this study was to investigate amateur music theatre singers (MTS)' perceptions of their current singing voice function according to evaluation of ability to sing easily (EASE) scores while involved in a musical theatre...
Medicine by Alexandros G. Sfakianakis
08:12
The role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.
The role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.: Related ArticlesThe role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.Eur J Surg Oncol. 2020 Jan 09;:Authors: Nixon IJ, Shah JP, Zafereo M, Simo RS, Hay ID, Suárez C, Zbären P, Rinaldo A, Sanabria A, Silver C, Mäkitie A, Vander Poorten V, Kowalski LP, Shaha AR, Randolph GW, Ferlito AAbstract...
Medicine by Alexandros G. Sfakianakis
08:11
Patterns of failure in patients with cutaneous head and neck melanoma.
Patterns of failure in patients with cutaneous head and neck melanoma.: Related ArticlesPatterns of failure in patients with cutaneous head and neck melanoma.Eur J Surg Oncol. 2020 Jan 01;:Authors: Bachar G, Tzelnick S, Amiti N, Gutman HAbstract INTRODUCTION: The incidence of head and neck melanoma is increasing. Various factors influence prognosis. OBJECTIVE: We sought to investigate the subgroup of patients with head and neck melanoma who fail primary treatment and to define the...
Medicine by Alexandros G. Sfakianakis
08:11
Management of the irradiated N0-neck during salvage pharyngo-laryngeal surgery.
Management of the irradiated N0-neck during salvage pharyngo-laryngeal surgery.: Related ArticlesManagement of the irradiated N0-neck during salvage pharyngo-laryngeal surgery.Eur J Surg Oncol. 2020 Jan 09;:Authors: Mazerolle P, Gorphe P, Vairel B, Dupret-Bories A, Temam S, Chaltiel L, Vergez SAbstract BACKGROUND: Salvage surgeries are challenging procedures, with an associated poor prognosis. Management of the N0 neck in those situations remains controversial. We aim to compare oncologic...
Medicine by Alexandros G. Sfakianakis
08:11
Cemiplimab in locally advanced cutaneous squamous cell carcinoma
Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial.: Related ArticlesCemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial.Lancet Oncol. 2020 Jan 14;:Authors: Migden MR, Khushalani NI, Chang ALS, Lewis KD, Schmults CD, Hernandez-Aya L, Meier F, Schadendorf D, Guminski A, Hauschild A, Wong DJ, Daniels GA, Berking C, Jankovic V, Stankevich E, Booth J, Li S, Weinreich...
Medicine by Alexandros G. Sfakianakis
08:11
Endothelial Autophagy: an Effective Target for Radiation-induced Cerebral Capillary Damage.
Endothelial Autophagy: an Effective Target for Radiation-induced Cerebral Capillary Damage.: Related ArticlesEndothelial Autophagy: an Effective Target for Radiation-induced Cerebral Capillary Damage.Sci Rep. 2020 Jan 17;10(1):614Authors: Ai X, Ye Z, Yao Y, Xiao J, You C, Xu J, Huang X, Zhong J, Fan M, Song X, Shi H, Zhang D, Zhao CAbstract Toxicity to central nervous system tissues is the common side effects for radiotherapy of brain tumor. The radiation toxicity has been thought to be related...
Medicine by Alexandros G. Sfakianakis
08:11
Internal Auditory Canal Variability: Anatomic Variation Affects Cisternal Facial Nerve Visualization.
Internal Auditory Canal Variability: Anatomic Variation Affects Cisternal Facial Nerve Visualization.: Related ArticlesInternal Auditory Canal Variability: Anatomic Variation Affects Cisternal Facial Nerve Visualization.Oper Neurosurg (Hagerstown). 2020 Jan 17;:Authors: Cohen MA, Abou-Al-Shaar H, Gozal YM, Karsy M, Alzhrani G, Shelton C, Couldwell WTAbstract BACKGROUND: The internal auditory canal (IAC) is an important landmark during surgery for lesions of the cerebellopontine angle. There...
Medicine by Alexandros G. Sfakianakis
08:11
Influence of proton pump inhibitor therapy on occurrence of voice prosthesis complications.
Influence of proton pump inhibitor therapy on occurrence of voice prosthesis complications.: Related ArticlesInfluence of proton pump inhibitor therapy on occurrence of voice prosthesis complications.Eur Arch Otorhinolaryngol. 2020 Jan 17;:Authors: Danic Hadzibegovic A, Kozmar A, Hadzibegovic I, Prgomet D, Danic DAbstract PURPOSE: It has been shown that the reflux of the gastric content to the proximal oesophagus influences incidence of voice prosthesis (VP) complications in laryngectomized...
Medicine by Alexandros G. Sfakianakis
08:10
Elective mucosal irradiation for head and neck cancer of unknown primary
Long-term results of elective mucosal irradiation for head and neck cancer of unknown primary in Chinese population: The EMICUP study.: Related ArticlesLong-term results of elective mucosal irradiation for head and neck cancer of unknown primary in Chinese population: The EMICUP study.Cancer Med. 2020 Jan 17;:Authors: Dou S, Li R, Zhang L, Wang Z, Xie L, Zhang C, Zhu GAbstract OBJECTIVE: Controversy still exists regarding the volume of radiation for head and neck cancer of unknown primary...
Medicine by Alexandros G. Sfakianakis
08:10
Anatomical assessment of trigeminal nerve tractography using diffusion MRI: A comparison of acquisition b-values and single- and multi-fiber tracking strategies.
Anatomical assessment of trigeminal nerve tractography using diffusion MRI: A comparison of acquisition b-values and single- and multi-fiber tracking strategies.: Related ArticlesAnatomical assessment of trigeminal nerve tractography using diffusion MRI: A comparison of acquisition b-values and single- and multi-fiber tracking strategies.Neuroimage Clin. 2020 Jan 08;25:102160Authors: Xie G, Zhang F, Leung L, Mooney MA, Epprecht L, Norton I, Rathi Y, Kikinis R, Al-Mefty O, Makris N, Golby AJ, O'Donnell...
Medicine by Alexandros G. Sfakianakis
08:10