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Πέμπτη 6 Αυγούστου 2020


Systemic treatment options for advanced biliary tract carcinoma.
Related Articles Systemic treatment options for advanced biliary tract carcinoma. J Gastroenterol. 2020 Aug 03;: Authors: Xie C, McGrath NA, Monge Bonilla C, Fu J Abstract Advanced biliary tract cancers (BTC) include a diverse collection of rare and heterogenous tumors with poor prognosis. The combination of gemcitabine and cisplatin is the established first-line therapy for advanced BTC. There are no accepted standard treatments in the second...
Rare Cancers
Wed Aug 05, 2020 13:06
Clear cell change in follicular adenoma of the thyroid. A diagnostic challenge.
Related Articles Clear cell change in follicular adenoma of the thyroid. A diagnostic challenge. Rom J Morphol Embryol. 2020;61(1):219-226 Authors: Val-Bernal JF, Martino M Abstract Clear cells in thyroid neoplasms can take two main forms: balloon-shaped and signet-ring cells. Balloon-shaped cell change in follicular adenoma is rare. A review of the literature has revealed only 20 previously published cases. We report herein a new case in the...
Rare Cancers
Wed Aug 05, 2020 13:06
Case for diagnosis. Penile lesion in HIV-negative patient.
Related Articles Case for diagnosis. Penile lesion in HIV-negative patient. An Bras Dermatol. 2020 Jun 26;: Authors: Ramos MC, Oliveira FB, Antonello VS, Boff AL Abstract We present the case of an HIV-negative man with asymptomatic penile erythematoviolaceous papules associated with similar slightly verrucous papules in the interdigital space of the right foot. A biopsy of the penile lesion confirmed Kaposi's sarcoma. No other causes of immunosuppression...
Rare Cancers
Wed Aug 05, 2020 13:06
The complexity of diagnosing sarcoma in a timely manner: perspectives of health professionals, patients, and carers in Australia.
Related Articles The complexity of diagnosing sarcoma in a timely manner: perspectives of health professionals, patients, and carers in Australia. BMC Health Serv Res. 2020 Aug 03;20(1):711 Authors: Weaver R, O'Connor M, Carey Smith R, Halkett GK Abstract BACKGROUND: Prolonged diagnosis intervals occur more often in rare cancers, such as sarcoma. Patients with a delayed diagnosis may require more radical surgery and have a reduced chance of...
Rare Cancers
Wed Aug 05, 2020 13:06
[Malignant gastrointestinal neuroectodermal tumor: clinicopathological analyses of four cases].
Related Articles [Malignant gastrointestinal neuroectodermal tumor: clinicopathological analyses of four cases]. Zhonghua Bing Li Xue Za Zhi. 2020 Aug 08;49(8):821-826 Authors: Huang HJ, He YH, Fan DG, Chen XY Abstract Objective: To investigate the clinicopathological features, diagnosis, differential diagnosis, and molecular alterations of malignant gastrointestinal neuroectodermal tumor (MGNET). Methods: Four cases of MGNET were collected...
Rare Cancers
Wed Aug 05, 2020 13:06
The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review.
Related Articles The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review. J Cancer Res Clin Oncol. 2020 Sep;146(9):2179-2188 Authors: Lin YL, Ma R, Li Y Abstract PURPOSE: Pseudomyxoma peritonei (PMP) is a rare clinical malignancy syndrome characterized by the uncontrollable accumulation of copious mucinous ascites in the peritoneal cavity, resulting in "jelly belly". The mechanism of tumor progression and mucin...
Rare Cancers
Wed Aug 05, 2020 13:06
Targeting glycolysis with 2-deoxy-D-glucose sensitizes primary cell cultures of renal cell carcinoma to tyrosine kinase inhibitors.
Related Articles Targeting glycolysis with 2-deoxy-D-glucose sensitizes primary cell cultures of renal cell carcinoma to tyrosine kinase inhibitors. J Cancer Res Clin Oncol. 2020 Sep;146(9):2255-2265 Authors: Simon AG, Esser LK, Ellinger J, Branchi V, Tolkach Y, Müller S, Ritter M, Kristiansen G, Muders MH, Mayr T, Toma MI Abstract PURPOSE: To investigate the synergistic effect of glycolysis inhibition on therapy answer to tyrosine kinase inhibitors...
Rare Cancers
Wed Aug 05, 2020 13:06
Retroperitoneal lymphatic malformation in a dog.
Related Articles Retroperitoneal lymphatic malformation in a dog. Acta Vet Scand. 2020 Feb 01;62(1):8 Authors: Driessen F, Cushing T, Baines SJ Abstract BACKGROUND: Lymphatic vascular malformations are rare findings in canine patients with six reports available in veterinary literature. Retroperitoneal cystic lymphatic malformations have not been described previously in canine patients and neither has the use of immunohistochemistry to determine...
Rare Cancers
Wed Aug 05, 2020 13:06
Clinicopathologic, Immunohistochemical, and Molecular Characteristics of Ovarian Serous Carcinoma With Mixed Morphologic Features of High-grade and Low-grade Serous Carcinoma.
Related Articles Clinicopathologic, Immunohistochemical, and Molecular Characteristics of Ovarian Serous Carcinoma With Mixed Morphologic Features of High-grade and Low-grade Serous Carcinoma. Am J Surg Pathol. 2020 03;44(3):316-328 Authors: Zarei S, Wang Y, Jenkins SM, Voss JS, Kerr SE, Bell DA Abstract Despite the current classification of high-grade serous carcinoma (HGSCA) and low-grade serous carcinoma (LGSCA) as mutually exclusive diseases...
Rare Cancers
Wed Aug 05, 2020 13:06
Advancements in Cancer Stem Cell Isolation and Characterization.
Related Articles Advancements in Cancer Stem Cell Isolation and Characterization. Stem Cell Rev Rep. 2019 12;15(6):755-773 Authors: Jariyal H, Gupta C, Bhat VS, Wagh JR, Srivastava A Abstract Occurrence of stem cells (CSCs) in cancer is well established in last two decades. These rare cells share several properties including presence of common surface markers, stem cell markers, chemo- and radio- resistance and are highly metastatic in nature;...
Rare Cancers
Wed Aug 05, 2020 13:06
Molecular Profiling of Noncoding Mutations Distinguishes Nevoid Melanomas From Mitotically Active Nevi in Pregnancy.
Related Articles Molecular Profiling of Noncoding Mutations Distinguishes Nevoid Melanomas From Mitotically Active Nevi in Pregnancy. Am J Surg Pathol. 2020 03;44(3):357-367 Authors: Jackett LA, Colebatch AJ, Rawson RV, Ferguson PM, Thompson JF, McCarthy SW, Wilmott JS, Scolyer RA Abstract The accurate recognition of subtle melanomas and their distinction from benign mimics is an oft-recurring diagnostic problem, critical for patient management....
Rare Cancers
Wed Aug 05, 2020 13:06
Unusual Variants of Follicular Lymphoma: Case-based Review.
Related Articles Unusual Variants of Follicular Lymphoma: Case-based Review. Am J Surg Pathol. 2020 03;44(3):329-339 Authors: Chapman JR, Alvarez JP, White K, Sanchez S, Khanlari M, Algashaamy K, Cassidy D, Peng JH, Fan YS, Alencar A, Alderuccio JP, Lossos IS, Vega F Abstract Follicular lymphoma (FL) is one of the most frequently diagnosed lymphomas in the United States and Europe. The definition of and basic approach to diagnosis and grading...
Rare Cancers
Wed Aug 05, 2020 13:06
Establishment and characterization of novel patient-derived extraskeletal osteosarcoma cell line NCC-ESOS1-C1.
Related Articles Establishment and characterization of novel patient-derived extraskeletal osteosarcoma cell line NCC-ESOS1-C1. Hum Cell. 2020 Jan;33(1):283-290 Authors: Kito F, Oyama R, Noguchi R, Hattori E, Sakumoto M, Endo M, Kobayashi E, Yoshida A, Kawai A, Kondo T Abstract Extraskeletal osteosarcoma (ESOS) is a rare mesenchymal malignancy producing osteoid and bone in soft tissue without skeletal attachment. ESOS exhibits chemoresistance...
Rare Cancers
Wed Aug 05, 2020 13:06
Establishment and characterization of a new malignant peritoneal mesothelioma cell line, KOG-1, from the ascitic fluid of a patient with pemetrexed chemotherapy resistance.
Related Articles Establishment and characterization of a new malignant peritoneal mesothelioma cell line, KOG-1, from the ascitic fluid of a patient with pemetrexed chemotherapy resistance. Hum Cell. 2020 Jan;33(1):272-282 Authors: Akahane T, Hirasawa A, Imoto I, Okubo A, Itoh M, Nanki Y, Yoshihama T, Tominaga E, Aoki D Abstract Malignant peritoneal mesothelioma (MPeM) is a rare and aggressive form of malignant mesothelioma. Sufficient biological...
Rare Cancers
Wed Aug 05, 2020 13:06
Endometrial Gastric (Gastrointestinal)-type Mucinous Lesions: Report of a Series Illustrating the Spectrum of Benign and Malignant Lesions.
Related Articles Endometrial Gastric (Gastrointestinal)-type Mucinous Lesions: Report of a Series Illustrating the Spectrum of Benign and Malignant Lesions. Am J Surg Pathol. 2020 03;44(3):406-419 Authors: Wong RW, Ralte A, Grondin K, Talia KL, McCluggage WG Abstract With the recent elucidation of gastric-type lesions in the female genital tract (especially in the cervix), occasional cases of endometrial adenocarcinoma displaying gastric (gastrointestinal)...
Rare Cancers
Wed Aug 05, 2020 13:06
Inhibition of Slug effectively targets leukemia stem cells via the Slc13a3/ROS signaling pathway.
Related Articles Inhibition of Slug effectively targets leukemia stem cells via the Slc13a3/ROS signaling pathway. Leukemia. 2020 02;34(2):380-390 Authors: Zhang Z, Li L, Wu C, Yin G, Zhu P, Zhou Y, Hong Y, Ni H, Qian Z, Wu WS Abstract Leukemia stem cells (LSCs) are the rare populations of acute myeloid leukemia (AML) cells that are able to initiate, maintain, and propagate AML. Targeting LSCs is a promising approach for preventing AML relapse...
Rare Cancers
Wed Aug 05, 2020 13:06
Debulking and three-dimensional reconstruction of a rare case of right atrium-ventricular angiosarcoma.
Related Articles Debulking and three-dimensional reconstruction of a rare case of right atrium-ventricular angiosarcoma. J Card Surg. 2019 Nov;34(11):1416-1419 Authors: Jiang Q, Yang X, Tan J, Huang K, Li W, Hu S Abstract A 48-year-old man presented with chest pain and ischemic manifestations according to an electrocardiogram due to coronary artery compression from a cardiac mass and was admitted to the emergency room and underwent extensive...
Rare Cancers
Wed Aug 05, 2020 13:06
Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review.
Related Articles Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review. Head Neck. 2019 12;41(12):4191-4198 Authors: Deng L, Wang R, Yang M, Li W, Zou L Abstract OBJECTIVES: Exploring the clinicopathological features of ameloblastic carcinoma (AC) and reviewing the literature to improve the diagnosis and treatment of the disease. MATERIALS AND METHODS: Clinical data and pathological features of 18...
Rare Cancers
Wed Aug 05, 2020 13:06
Primary cardiac synovial sarcoma: A review correlating outcomes with surgery and adjuvant therapy.
Related Articles Primary cardiac synovial sarcoma: A review correlating outcomes with surgery and adjuvant therapy. J Card Surg. 2019 Nov;34(11):1321-1327 Authors: Coli A, Cassano A, Novello M, Ranelletti FO, Lauriola L Abstract BACKGROUND: Cardiac synovial sarcoma (CSS) is an extremely rare malignant tumor with a severe prognosis, due to frequent relapses and metastases. To obtain useful information for treatment protocols, we analyzed survival...
Rare Cancers
Wed Aug 05, 2020 13:06
Adenocarcinoma masked by re-expansion pulmonary edema after chest drainage for pneumothorax.
Related Articles Adenocarcinoma masked by re-expansion pulmonary edema after chest drainage for pneumothorax. Thorac Cancer. 2019 09;10(9):1834-1836 Authors: Jung JJ, An HJ, Jeon KN, Kim JW Abstract Re-expansion pulmonary edema is a rare complication that may occur after chest drainage performed for pneumothorax. This condition manifests as areas of ground-glass opacities (GGO) and septal thickening on imaging studies. In the case reported...
Rare Cancers
Wed Aug 05, 2020 13:06
Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors.
Related Articles Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors. Haematologica. 2019 12;104(12):2400-2409 Authors: Nteliopoulos G, Bazeos A, Claudiani S, Gerrard G, Curry E, Szydlo R, Alikian M, Foong HE, Nikolakopoulou Z, Loaiza S, Khorashad JS, Milojkovic D, Perrotti D, Gale RP, Foroni L, Apperley JF Abstract There are no validated molecular biomarkers...
Rare Cancers
Wed Aug 05, 2020 13:06
Incidence, Clinical Features, and Outcomes of Langerhans Cell Sarcoma in the United States.
Related Articles Incidence, Clinical Features, and Outcomes of Langerhans Cell Sarcoma in the United States. Clin Lymphoma Myeloma Leuk. 2019 07;19(7):441-446 Authors: Tella SH, Kommalapati A, Rech KL, Go RS, Goyal G Abstract BACKGROUND: Limited knowledge exists on the incidence, treatment patterns, and long-term outcomes of Langerhans cell sarcoma (LCS) in the United States. PATIENTS AND METHODS: We performed a retrospective study...
Rare Cancers
Wed Aug 05, 2020 13:06
A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.
Related Articles A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations. Sci Rep. 2019 01 29;9(1):842 Authors: Nixon AML, Duque A, Yelle N, McLaughlin M, Davoudi S, Pedley NM, Haynes J, Brown KR, Pan J, Hart T, Gilbert PM, Singh SK, O'Brien CA, Sidhu SS, Moffat J Abstract Cell surface antigen discovery is of great interest for biomedical research both for isolation of rare...
Rare Cancers
Wed Aug 05, 2020 13:06
Bladder Malakoplakia Simulating Neoplasm in a Young Girl: Report of a Case and Review of Literature.
Related Articles Bladder Malakoplakia Simulating Neoplasm in a Young Girl: Report of a Case and Review of Literature. Urol J. 2019 12 24;16(6):614-615 Authors: Rabani SMR, Rabani SH Abstract Malakoplakia is a granulomatous disorder caused by infectious process. It was described by Von Hanseman in 1901 for the first time and then by Michaelis and Gutman in 1902.  Although the most frequent site of involvement is genitourinary tract, various...
Rare Cancers
Wed Aug 05, 2020 13:06
Multifocal mesenchymal hamartoma of the chest wall in a newborn.
Related Articles Multifocal mesenchymal hamartoma of the chest wall in a newborn. Turk J Pediatr. 2019;61(6):975-978 Authors: Yavuz ÖÖ, Özcan HN, Çınar HG, Oğuz B, Haliloğlu M Abstract Özkale Yavuz Ö, Özcan HN, Çınar HG, Oğuz B, Haliloğlu M. Multifocal mesenchymal hamartoma of the chest wall in a newborn. Turk J Pediatr 2019; 61: 975-978. Mesenchymal hamartoma of the chest wall is an extremely rare, benign chondro-osseous chest wall tumor which...
Rare Cancers
Wed Aug 05, 2020 13:06

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