Abstract Smoking has been consistently associated with the risk of colorectal cancer (CRC) in Western populations; however, evidence is limited and inconsistent in Asian people. To assess the association of smoking status, smoking intensity, and smoking cessation with colorectal risk in the Japanese population, we performed a pooled analysis of ten population‐based cohort studies. Study‐specific hazard ratios (HR) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards model...
Wed Aug 05, 2020 20:45
Abstract The conclusion derived from the information provided in this review is that disseminating tumor cells (DTC) collaborate with the microenvironment of a future metastatic organ site in the establishment of organ‐specific metastasis. We review the basic principles of site‐specific metastasis and the contribution of the cross talk between DTC and the microenvironment of metastatic sites (metastatic microenvironment – MME) to: the establishment of the organ‐specific pre‐metastatic niche; the...
Wed Aug 05, 2020 20:45
Abstract Viral hepatitis is the primary cause of liver diseases, among which liver cancer is the leading cause of death from cancer. However, this cancer is often diagnosed in the later stages, which makes treatment difficult or even impossible. This study applied deep learning (DL) models for the early prediction of liver cancer in a hepatitis cohort. In this study, we surveyed one million random samples from the National Health Insurance Research Database (NHIRD) to analyze viral hepatitis patients...
Wed Aug 05, 2020 20:44
Abstract The epidemiological literature reports inconsistent associations between consumption or circulating concentrations of micro‐nutrients and breast cancer risk. We investigated associations between genetically predicted concentrations of 11 micro‐nutrients (beta‐carotene, calcium, copper, folate, iron, magnesium, phosphorus, selenium, vitamin B6, vitamin B12 and zinc) and breast cancer risk using Mendelian randomization (MR). A two‐sample MR study was conducted using 122,977 women with breast...
Wed Aug 05, 2020 20:43
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