Related Articles Peripheral nerve block use in inpatient and outpatient shoulder arthroplasty: a population-based study evaluating utilization and outcomes. Reg Anesth Pain Med. 2020 Aug 03;: Authors: Chan JJ, Cirino CM, Vargas L, Poeran J, Zubizarreta N, Mazumdar M, Galatz LM, Cagle PJ Abstract BACKGROUND: Peripheral nerve block (PNB) is an effective pain management option after shoulder arthroplasty with increasing popularity over the...
Wed Aug 05, 2020 16:26
Related Articles [Sexual and emotional life after allogeneic hematopoietic stem cell transplant: Guidelines and patient booklet from the Francophone Society of Bone marrow Transplant and Cellular therapy (SFGM-TC)]. Bull Cancer. 2020 Jul 31;: Authors: Alsuliman T, Baylet C, Casabona A, Dann MP, De Bentzmann N, Fontoura ML, Genty C, Huynh A, Ibled D, Mercier L, Poirot C, Porcheron S, Tourette-Turgis C, Vernant JP, Vexiau-Robert D, Yakoub-Agha I, Nguyen S ...
Wed Aug 05, 2020 14:28
Related Articles Pentamethylquercetin Inhibits Hepatocellular Carcinoma Progression and Adipocytes-induced PD-L1 Expression via IFN-γ Signaling. Curr Cancer Drug Targets. 2020 Jul 30;: Authors: Li Z, Gao WQ, Wang P, Wang TQ, Xu WC, Zhu XY, Liu H Abstract BACKGROUND: Obesity is a significant risk factor for the development of types of cancer. Programmed death 1 and its ligand programmed death ligand 1 (PD-L1) play a crucial role in tumor immune...
Wed Aug 05, 2020 16:35
Related Articles MALAT1 as a Versatile Regulator of Cancer: Overview of the updates from Predatory role as Competitive Endogenous RNA to Mechanistic In-sights. Curr Cancer Drug Targets. 2020 Jul 30;: Authors: Farooqi AA, Legaki E, Gazouli M, Rinaldi S, Berardi R Abstract Central dogma of molecular biology has remained cornerstone of classical molecular biology but serendipitous discovery of microRNAs (miRNAs) in nematodes paradigmatically shifted...
Wed Aug 05, 2020 16:35
Related Articles Advances in Regulating Tumorigenicity and Metastasis of Cancer through TrkB Signaling. Curr Cancer Drug Targets. 2020 Jul 30;: Authors: Zou W, Hu X, Jiang L Abstract The clinical pathology of various human malignancies is supported by tropomyosin receptor kinase (Trk) B TrkB which is a specific binding receptor of the brain-derived neurotrophic factor (BDNF).TrkB and TrkB fusion proteins have been observed to be over-expressed...
Wed Aug 05, 2020 16:35
Antimicrobial peptides: a promising strategy for lung cancer drug discovery? Expert Opin Drug Discov. 2020 Aug 04;:1-12 Authors: Zandsalimi F, Talaei S, Noormohammad Ahari M, Aghamiri S, Raee P, Roshanzamiri S, Yarian F, Bandehpour M, Zohrab Zadeh Z Abstract INTRODUCTION: Antimicrobial peptides (AMPs), also called host defense peptides (HDPs), are identified in almost any form of life, which play an important role in innate immune systems....
Wed Aug 05, 2020 16:51
Drug discovery strategies for modulating oxidative stress in gastrointestinal disorders. Expert Opin Drug Discov. 2020 Aug 04;:1-33 Authors: Mousavi T, Hadizadeh N, Nikfar S, Abdollahi M Abstract INTRODUCTION: Due to the ever-growing incidence of gastrointestinal disorders accompanied by substantial economic impact, it is of great importance to manage these conditions globally. Since the significant role of oxidative stress has been proved...
Wed Aug 05, 2020 16:51
Robotic pancreaticoduodenectomy in elderly and younger patients: A Retrospective Cohort Study. Int J Surg. 2020 Aug 01;: Authors: Liu Q, Zhao Z, Zhang X, Zhao G, Tan X, Gao Y, Lau WY, Liu R Abstract BACKGROUND: Robotic pancreaticoduodenectomy (RPD) has gradually been accepted as it has overcome some of the limitations of laparoscopic surgery. Outcomes following RPD in elderly patients are still uncertain. This study aimed to evaluate the...
Wed Aug 05, 2020 13:45
Letter to the Editor on "Absorbable versus non-absorbable tacks for mesh fixation in laparoscopic ventral hernia repair: A systematic review and meta-analysis" (Int J Surg 2018;53:184-92). Int J Surg. 2020 Aug 01;: Authors: Friis-Andersen H PMID: 32750490 [PubMed - as supplied by publisher]
Wed Aug 05, 2020 13:45
Related Articles Q-switched 532 nm Nd:YAG laser therapy for physiological lip hyperpigmentation: novel classification, efficacy, and safety. J Dermatolog Treat. 2020 Aug 04;:1-21 Authors: Altalhab S, Aljamal M, Mubki T, AlNomair N, Algoblan S, Alalola A, AlJasser MI, Alissa A Abstract BACKGROUND: Physiological lip hyperpigmentation (PLH) is a common cosmetic concern in the Middle East and Asia. It is characterized by homogeneous symmetric diffuse...
Wed Aug 05, 2020 16:53
Related Articles Change of dermatological practice after the COVID-19 outbreak resolves. J Dermatolog Treat. 2020 Aug 04;:1-3 Authors: Gao C, Liu B, Xie Y, Wu Z Abstract AIM: Dermatological care has already been deeply impacted by the coronavirus disease-2019 (COVID-19) epidemic. The consequences may continue long after the epidemic resolves. In this study, we aimed to evaluate the change of dermatological practice since the COVID-19 outbreak...
Wed Aug 05, 2020 16:53
Related Articles Real-life efficiency and safety comparison study of emollient ointment based on glycerophosphoinositol (GPI) salt of choline and other emollient products in patients with atopic dermatitis. J Dermatolog Treat. 2020 Aug 04;:1-12 Authors: Marko M, Pawliczak R Abstract INTRODUCTION: The aim of this study was to investigate the effectiveness and safety of emollient preparations in comparison with the emollient ointment containing...
Wed Aug 05, 2020 16:53
Related Articles The psychological, social and educational impact of prominent ears: A systematic review. J Plast Reconstr Aesthet Surg. 2020 May 26;: Authors: Jones ES, Gibson JAG, Dobbs TD, Whitaker IS Abstract BACKGROUND: Prominent ears are the most common congenital abnormality of the head and neck, occurring in 5% of the Caucasian population. Facial disfigurement can cause psychosocial distress, low self-esteem and varying levels of social...
Wed Aug 05, 2020 14:15
Blue Light Laser Results in Less Vocal Fold Scarring Compared to KTP Laser in Normal Rat Vocal Folds. Laryngoscope. 2020 Aug 04;: Authors: Lin RJ, Iakovlev V, Streutker C, Lee D, Al-Ali M, Anderson J Abstract OBJECTIVES: Preliminary investigations suggest that a novel blue light (BL) laser with a wavelength of 445 nm is comparable to the commonly utilized potassium titanyl phosphate (KTP) laser (532 nm) for treatment of various laryngeal pathologies....
Wed Aug 05, 2020 16:41
A Rare Case of Primary Neuroendocrine Carcinomas in the Ear and Throat and Review of Literatures. Ear Nose Throat J. 2020 Aug 04;:145561320943340 Authors: Ma T, Wang C, Qin X, Zhang T Abstract The neuroendocrine carcinomas (NECs) of the head and neck are rare. The purpose of this article is to explore the diagnosis and treatment of NECs in the ear and larynx. We report a case of a patient with NECs found in the ear and throat simultaneously,...
Wed Aug 05, 2020 16:41
Related Articles Comparison of real-ear insertion gains in Japanese-speaking individuals wearing hearing aids with DSLv5 and NAL-NL2. Auris Nasus Larynx. 2020 Jul 31;: Authors: Furuki S, Sano H, Kurioka T, Ogiwara A, Nakagawa T, Inoue R, Umehara S, Hara Y, Suzuki K, Yamashita T Abstract OBJECTIVE: We used real-ear insertion gain (REIG), with the international speech test signal (ISTS), to evaluate the amplifying characteristics of hearing aids,...
Wed Aug 05, 2020 16:41
Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy. J Clin Oncol. 2020 Aug 04;:JCO2000549 Authors: León-Castillo A, de Boer SM, Powell ME, Mileshkin LR, Mackay HJ, Leary A, Nijman HW, Singh N, Pollock PM, Bessette P, Fyles A, Haie-Meder C, Smit VTHBM, Edmondson RJ, Putter H, Kitchener HC, Crosbie EJ, de Bruyn M, Nout RA, Horeweg N, Creutzberg CL, Bosse T, TransPORTEC consortium...
Wed Aug 05, 2020 13:38
Serious Illness Conversations With Outpatient Oncology Clinicians: Understanding the Patient Experience. JCO Oncol Pract. 2020 Aug 04;:JOP1900765 Authors: Kumar P, Wixon-Genack J, Kavanagh J, Sanders JJ, Paladino J, O'Connor NR Abstract PURPOSE: Guidelines recommend earlier advance care planning discussions focused on goals and values (serious illness communication) among oncology patients. We conducted a prospective, cross-sectional quality...
Wed Aug 05, 2020 13:38
Evolution of the role of haploidentical stem cell transplantation: past, present, and future. Expert Rev Hematol. 2020 Aug 04;:1-16 Authors: Kwon M, Bailén R, Díez-Martín JL Abstract INTRODUCTION: The accessibility to haplo-donors has led to an increase in the number of haplo-HSCT worldwide. A systematic search of the PubMed database between 2000 to present was performed. AREAS COVERED: In this review, the authors discussed the most...
Wed Aug 05, 2020 13:38
Related Articles Phase 2 study of afatinib among patients with recurrent and/or metastatic esophageal squamous cell carcinoma. Cancer. 2020 Aug 04;: Authors: Hong MH, Heo SG, Lee YG, Kim HS, Park KU, Kim HG, Ko YH, Chung IJ, Min YJ, Kim MK, Kim KR, Yoo J, Kim TM, Kim HR, Cho BC Abstract BACKGROUND: The objective of the current study was to investigate the clinical activity of, safety of, and predictive biomarkers for afatinib, an irreversible...
Wed Aug 05, 2020 13:38
Related Articles Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months. Oncol Ther. 2020 Aug 04;: Authors: de Las Heras B, Saini KS, Boyle F, Ades F, de Azambuja E, Bozovic-Spasojevic I, Romano M, Capelan M, Prasad R, Pattu P, Massard C, Portera C, Saini ML, Singh BP, Venkitaraman R, McNally R, Leone M, Grande E, Gupta S Abstract The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact...
Wed Aug 05, 2020 13:38
Related Articles Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing. Epigenetics. 2020 Aug 04;: Authors: Zhang Z, Wang Q, Zhang M, Zhang W, Zhao L, Yang C, Wang B, Jiang K, Ye Y, Shen Z, Wang S Abstract Accumulating evidence has demonstrated that N6-methyladenosine (m6A) plays important roles in various cancers, making it essential to profile m6A modifications at a transcriptome-wide scale...
Wed Aug 05, 2020 13:38
Related Articles Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumors: current and future application of "epidrugs". Epigenetics. 2020 Aug 04;: Authors: Cardoso AR, Lobo J, Miranda-Gonçalves V, Henrique R, Jerónimo C Abstract Testicular germ cell tumors (TGCTs) are heterogeneous neoplasms mostly affecting young-adult men. Despite high survival rates, some patients with disseminated disease acquire cisplatin resistance,...
Wed Aug 05, 2020 13:38
Related Articles Vicenin-2 Treatment Attenuated the Diethylnitrosamine-Induced Liver Carcinoma and Oxidative Stress through Increased Apoptotic Protein Expression in Experimental Rats. J Environ Pathol Toxicol Oncol. 2020;39(2):113-123 Authors: Zhang C, Chen Y, Zhang M, Xu C, Gong G, Veeraraghavan VP, Bolla SR, Li Y Abstract Liver cancer or hepatocellular carcinoma is considered to be the third leading cause of death among all other cancers....
Wed Aug 05, 2020 13:38
Related Articles Personalized Treatment Selection and Disease Monitoring Using Circulating Tumor DNA Profiling in Real-World Cancer Patient Management. Diagnostics (Basel). 2020 Aug 02;10(8): Authors: Wehrle J, Philipp U, Jolic M, Follo M, Hussung S, Waldeck S, Deuter M, Rassner M, Braune J, Rawluk J, Greil C, Waller CF, Becker H, Duque-Afonso J, Illert AL, Fritsch RM, Meiss F, Duyster J, von Bubnoff N, Scherer F Abstract BACKGROUND: Circulating...
Wed Aug 05, 2020 13:38
Related Articles KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma. Protein Cell. 2020 Aug 03;: Authors: Wei S, Dai M, Zhang C, Teng K, Wang F, Li H, Sun W, Feng Z, Kang T, Guan X, Xu R, Cai M, Xie D Abstract Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is the fourth-leading cause of cancer-related deaths worldwide. HCC is refractory to many standard...
Wed Aug 05, 2020 13:38
Related Articles Development of a Risk Score and Nomogram to Predict Individual Benefit Attained from the Addition of Adjuvant Chemotherapy in the Treatment of Stage II Colon Cancer. J Gastrointest Surg. 2020 Aug 03;: Authors: Nelson DW, Merritt C, Chang SC, Grunkemeier G, Steele SR, Goldfarb M Abstract BACKGROUND: Current guidelines recommend considering adjuvant chemotherapy (AC) for stage II colon cancer (CC) with poor prognostic clinicopathologic...
Wed Aug 05, 2020 13:38
Related Articles Total Parietal Peritonectomy Can Be Performed with Acceptable Morbidity for Patients with Advanced Ovarian Cancer After Neoadjuvant Chemotherapy: Results From a Prospective Multi-centric Study. Ann Surg Oncol. 2020 Aug 03;: Authors: Bhatt A, Kammar P, Sinukumar S, Parikh L, Jumle N, Shaikh S, Mehta S Abstract BACKGROUND: Total parietal peritonectomy (TPP) removes areas of "normal-appearing" parietal peritoneum bearing microscopic...
Wed Aug 05, 2020 13:38
Related Articles Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nat Med. 2020 Aug 03;: Authors: Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, Haase D, Creignou M, Germing U, Zhang Y, Gundem G, Sarian A, van de Loosdrecht AA, Jädersten M, Tobiasson M, Kosmider...
Wed Aug 05, 2020 13:38
Related Articles Central nervous system miliary metastasis in breast cancer: a case series analysis and proposed identification criteria of a rare metastasis subtype. Br J Cancer. 2020 Aug 04;: Authors: Bashour SI, Ibrahim NK, Schomer DF, Hess KR, Gao C, Tripathy D, Fuller GN Abstract BACKGROUND: CNS miliary metastasis (MiM) is poorly recognised in breast and other malignancies. Given its rarity, little epidemiologic, radiographic and clinical...
Wed Aug 05, 2020 13:38
Related Articles Miliary breast cancer brain metastasis: a rare and aggressive form of central nervous system metastasis. Br J Cancer. 2020 Aug 04;: Authors: Mills MN, Ahmed KA Abstract Although breast cancer brain metastasis is an increasingly common occurrence, relatively little is known about miliary brain metastases, a rare subtype that presents unique diagnostic and management challenges. The present study from Bashour et al. proposes the...
Wed Aug 05, 2020 13:38
Related Articles Application of exosomes as liquid biopsy in clinical diagnosis. Signal Transduct Target Ther. 2020 Aug 03;5(1):144 Authors: Zhou B, Xu K, Zheng X, Chen T, Wang J, Song Y, Shao Y, Zheng S Abstract Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small extracellular vesicles with sizes between 30-150 nm. They...
Wed Aug 05, 2020 13:38
Related Articles Future role for adoptive T-cell therapy in checkpoint inhibitor-resistant metastatic melanoma. J Immunother Cancer. 2020 Jul;8(2): Authors: Borch TH, Andersen R, Ellebaek E, Met Ö, Donia M, Marie Svane I Abstract Personalized cell therapy targeting tumor antigens with expanded tumor-infiltrating lymphocytes (TILs) has shown great promise in metastatic melanoma (MM) since the 90s. However, MM was first-in line to benefit from...
Wed Aug 05, 2020 13:38
Related Articles Spine and Non-spine Bone Metastases - Current Controversies and Future Direction. Clin Oncol (R Coll Radiol). 2020 Jul 31;: Authors: Challapalli A, Aziz S, Khoo V, Kumar A, Olson R, Ashford RU, Gabbar OA, Rai B, Bahl A Abstract Bone is a common site of metastases in advanced cancers. The main symptom is pain, which increases morbidity and reduces quality of life. The treatment of bone metastases needs a multidisciplinary approach,...
Wed Aug 05, 2020 13:38
Related Articles Trends of the incidence of drug use disorders from 1990 to 2017: an analysis based on the Global Burden of Disease 2017 data. Epidemiol Psychiatr Sci. 2020 Aug 04;29:e148 Authors: Pan Z, Zhang J, Cheng H, Bu Q, Li N, Deng Y, Zhou L, Dai Z, Lyu J Abstract AIM: Drug use disorders are an important issue worldwide. Systematic attempts to estimate the global incidence of drug use disorders are rare. We aimed to determine the incidence...
Wed Aug 05, 2020 13:38
Related Articles Survival prediction model for patients with mycosis fungoides/Sezary syndrome. Future Oncol. 2020 Aug 04;: Authors: Zhu L, Han X, Liu Z, Leng S, Shan N, Lv X, Lu K, Hun S, Wu Y, Liu X Abstract Aim: A nomogram was constructed to forecast the overall survival (OS) of patients with mycosis fungoides/Sezary syndrome. Patients & Methods: The clinicopathological information of patients was obtained from the Surveillance, Epidemiology,...
Wed Aug 05, 2020 13:38
Related Articles Clonal hematopoiesis and risk of acute myeloid leukemia. Haematologica. 2019 12;104(12):2410-2417 Authors: Young AL, Tong RS, Birmann BM, Druley TE Abstract Nearly all adults harbor acute myeloid leukemia (AML)-related clonal hematopoietic mutations at a variant allele fraction (VAF) of ≥0.0001, yet relatively few develop hematologic malignancies. We conducted a nested analysis in the Nurses' Health Study and Health Professionals...
Wed Aug 05, 2020 13:38
Related Articles Cancer does not care about coronavirus. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 08;: Authors: Lubek JE PMID: 32747212 [PubMed - as supplied by publisher]
Wed Aug 05, 2020 13:57
Related Articles A Randomized Controlled Trial of Dexamethasone as a Prophylactic Treatment for Subglottic Stenosis in a Rabbit Model. Ann Otol Rhinol Laryngol. 2020 Aug 04;:3489420946773 Authors: Wistermayer P, Escalante D, McIlwain W, Rogers DJ Abstract OBJECTIVE: Iatrogenic injury is a common cause of subglottic stenosis (SGS). We investigated the role of pre-injury dexamethasone as a preventive treatment for iatrogenic subglottic stenosis....
Wed Aug 05, 2020 13:09
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