Background: Ceritinib (CERI) has demonstrated in the ASCEND-4 phase III trial to improve progression free survival (PFS) compared with chemotherapy in previously untreated lymphoma kinase-positive (ALK+) advanced non-small cell lung cancer (NSCLC). The ASCEND-8 bioequivalence trial confirmed similar pharmacokinetics and better safety profile with a lower dose of CERI at 450mg daily with food. Our objective is to assess the cost-effectiveness of CERI versus crizotinib in the treatment of ALK+ NSCLC in Hong Kong (HK).
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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