Cortical networks are disturbed in people with cirrhosis even in the absence of neuropsychometric impairment

The term 'hepatic encephalopathy' is used to describe the spectrum of neuropsychiatric change which commonly complicates the course of cirrhosis (Vilstrup et al., 2014). People with cirrhosis with clinically apparent impairment in mental and motor performance, for which there is no other discernible cause, are classified as having overt hepatic encephalopathy. Those with no apparent clinical neuropsychiatric deficits who nevertheless show neuropsychometric or neurophysiological abnormalities are classified as having minimal hepatic encephalopathy (Vilstrup et al., 2014).

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