Late Sequelae of Childhood and Adolescent Nasopharyngeal Carcinoma Survivors after Radiotherapy

This study examined the long-term sequelae of children and adolescent nasopharyngeal carcinoma (NPC) survivors after radiotherapy. Comparing with convention radiotherapy treatment (CRT), intensity-modulated radiotherapy treatment (IMRT) can potentially ameliorate xerostomia, dysphagia and otitis media in survivors. Besides, patients younger than 10 years old had a higher cumulative incidence (CI) of blurred vision. Moreover, a dose of more than 72 Gray (Gy) to primary tumor increased the CI of hearing loss, lalopathy and cranial nerve injury.

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