Issue Highlights

Studies have shown a positive association between systemic markers of inflammation and the risk of future cardiovascular disease. It is believed that this risk is mediated by prothrombotic changes in the vasculature as a response to inflammation. Systemic inflammatory diseases such as inflammatory bowel disease (IBD) may increase the risk for coronary artery disease by this mechanism, although prior epidemiologic studies show mixed results. In this issue of Clinical Gastroenterology and Hepatology, Aniwan and colleagues1 evaluated the risk of acute myocardial infarction and heart failure in patients with ulcerative colitis (UC) and Crohn's disease.

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