What Factors Predict Fluid Responsiveness in Hemodynamically Unstable Patients?

Fifty studies were identified, including 2,260 patients. The most commonly reported cause of hemodynamic instability was sepsis (median 71%; interquartile range 60% to 94%), with a median 66% of patients (interquartile range 50% to 85%) receiving vasopressors. Most findings on physical examination were not predictive, including skin turgor, capillary refill time, jugular venous distention, appearance of mucous membranes, pulmonary auscultation, and presence or absence of leg edema, ascites, and pleural effusions.

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