IMP3: a potential diagnostic and therapeutic biomarker for cancers

Immunohistochemical expression levels of insulin-like growth factor II mRNA-binding protein 3 (IMP3) have been reported to be implicated in the migration, invasion, and metastasis of various cancers. However, IMP3 expression signatures and function profiles in human colorectal cancer (CRC) are still largely elusive. Surprisingly, we read with great interest the recently published work by Wei et al. [1], demonstrating that IMP3 is significantly highly regulated in patients with CRC resection specimens.

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