Cardiac-sparing whole lung imrt in patients with pediatric tumors and lung metastasis: Final report of a prospective multicenter clinical trial

A prospective clinical trial was conducted to demonstrate the feasibility of whole lung IMRT, study its dosimetric advantages and assess the short term clinical outcomes in children with lung metastasis. Real time central QA review and pre-approval was obtained. Cardiac sparing IMRT was feasible in all patients and showed improved 4D lung dose coverage and significant reduction in cardiac doses compared to standard techniques. One patient developed cardiac and pulmonary toxicity 5 years after treatment.

https://ift.tt/2wpmNMJ