A Deep Look into the Future of Quantitative Imaging in Oncology: A Statement of Working Principles and Proposal for Change

The rapid growth of quantitative imaging research in recent years has resulted in a number of publications with sub-optimal methods to provide generalizable results. We believe the fields of quantitative imaging and radiomics require renewed focus on optimal study design/reporting practices, standardization, interpretability, data sharing and clinical trials. In this critical review, we propose fundamental changes to the scientific approach to ensure high-impact research and the development of actionable prediction models that will yield more meaningful applications.

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