Impact of whole lung irradiation on survival outcome in patients with lung relapsed Ewing sarcoma

Whole lung irradiation (WLI) demonstrated potential improvements in survival outcomes in patients with isolated lung relapse of a Ewing sarcoma (EwS), and it additionally appears to be tolerated and safe for both pediatric and young adult patients. The primary tumor site and response of pulmonary lesions to chemotherapy are significant prognostic factors for survival following WLI. Without a randomized prospective analysis, the WLI should be considered for treating pulmonary relapsed EwS.

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