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Τρίτη 3 Ιουλίου 2018

Elevated DSN1 expression is associated with poor survival in patients with hepatocellular carcinoma

Dosage suppressor of Nnf1 (DSN1) is a component of the kinetochore protein complex that is required for proper chromosome segregation. Some studies have explored that DSN1 is related to colorectal cancer progression. However, the role of DSN1 in hepatocellular carcinoma (HCC) remains unknown. This study aimed to explore DSN1 expression in HCC tissues and investigated DSN1 functions in HCC cells. We obtained data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) to analyze DSN1 expression in HCC.

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