Association between Mismatch Negativity and Voxel-Based Brain Volume in Schizophrenia

Mismatch negativity (MMN), a type of event-related potential (ERP), is generated when a discernable change occurs in a series of repetitive standard stimuli (Naatanen et al., 1978). MMN represents the pre-attentive process of auditory discrimination and is associated with the function of auditory memory and involuntary attention shifting (Naatanen et al., 1979, Javitt et al., 1995, Naatanen et al., 2007). MMN deficit is extensively observed in schizophrenia patients (Shelley et al., 1991, Javitt et al., 1993, Umbricht et al., 2005).

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