Risk of Radiation Vasculopathy and Stroke in Pediatric Patients Treated with Proton Therapy for Brain and Skull Base Tumors

Childhood cancer survivors are at risk of vasculopathy. This review of 651 children treated with proton therapy estimates the rate of serious vasculopathy is 2.6% at 3 years following treatment. Young age and doses ≥54 CGE to the suprasellar region are the dominant risk factors.

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