A Small Window of Opportunity When Disease Is Limited in Extensive-Stage Small Cell Lung Cancer?

Prophylactic cranial irradiation (PCI) and consolidative chest radiation therapy (RT) improve survival in extensive-stage small cell lung cancer (SCLC) patients who have responded to standard platinum/etoposide-based chemotherapy. Because these RT-based additions represent the only advances in this disease over the last decade, the appropriateness of more-aggressive strategies that also preserve quality of life is of considerable interest.

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