P3-1-2. Assessment of the atypical cortico-cortical evoked potentials

Cortico-cortical evoked potential (CCEP) has been widely used to probe brain network.Typically CCEP waveform consists of two negative potentials, N1 (peak: 10–50 ms) and N2 (peak: 100–500 ms). We, however, occasionally encounter atypical responses, such as those with prolonged N1 peak latency. We attempt to classify these atypical patterns and clarify their anatomical distribution. We retrospectively reviewed CCEP responses in two patients with intractable focal epilepsy, in whom CCEPs were obtained bystimulating all the implanted subdural electrodes (IRB#443).

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