The Interplay Between Nonalcoholic Fatty Liver Disease and Atherosclerotic Heart Disease

Abstract

Nonalcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease, exists in two predominant histological subtypes: nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). NASH is the clinically aggressive variant with higher risk of fibrosis progression and mortality. The leading cause of mortality in patients with NAFLD is cardiovascular disease (CVD), and is linked to diagnosis of NASH and severity of hepatic fibrosis.

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