Early Endovascular Thrombectomy for Large Vessel Ischemic Stroke Reduces Disability at 90 Days

Abstract

Anterior circulation large vessel occlusion (LVO) of the internal carotid or middle cerebral artery is one of the most devastating ischemic stroke subtypes. Prior to 2015, evidence supporting endovascular thrombectomy for acute ischemic stroke was limited. This was due to multiple factors, including low recanalization rates with previous generation thrombectomy devices, inadequate neuroimaging inclusion criteria (patients enrolled in trials lacked target LVO and/or had large pre‐existing core infarcts), and selection bias—patients considered most likely to benefit from thrombectomy underwent the procedure outside of clinical trials.

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