Increased Emg Intermuscular Coherence and Reduced Signal Complexity in Parkinson’s Disease

The severity of the symptoms of Parkinson's disease (PD) are currently clinically evaluated using subjective scores such as the Movement Disorders Society Unified-Parkinson's-Disease-Rating-Scale (MDS-UPDRS) (Goetz et al., 2008). The semi-quantitative score, MDS-UPDRS III, provides a macro view of motor control without characterising specific patient kinematics. There is a recognised need for more quantitative measures to evaluate motor symptoms in PD which can provide insights into changes in neural control and provide an objective biomarker for diagnosis.

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