A technique to rapidly generate synthetic CT for MRI-guided online adaptive re-planning: an exploratory study

A method to quickly create synthetic CT (sCT) by transferring rED from patient's own CT based on deformable registration of CT and MRI with special consideration of bone and air regions has been developed. The sCT generated is more accurate than that from the commonly-used bulk density assignment but without the need for multiple MR sequences. The method can be fully automated, thus, applicable for online adaptive replanning.

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