The clinical and dosimetric impact of real-time target tracking in pancreatic SBRT

Motion is a major source of uncertainty and error in ablative treatment of pancreatic tumors. We retrospectively analyzed a large cohort of patients treated with Stereotactic Body Radiotherapy under real-time, fiducial-based kV image guidance. We found that using these real-time images to make corrections to the tumor position resulted in significant dosimetric benefits to the tumor. We also characterized the workflow changes required to implement real-time target tracking.

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