Neuromodulation of lower limb motor responses with transcutaneous lumbar spinal cord direct current stimulation

The spinal cord (SC) is a complex structure that contains its own neuronal circuits modulated by higher encephalic function. The motor information descends via the corticospinal tracts to synapse with the alpha and gamma motor neurons located in the anterior horns, directly or via spinal interneurons. SC is not only a bidirectional communication pathway between brain and the periphery, but it also contains local circuits known to permit locomotion movements and segmental spinal reflexes (Iglesias et al., 2008).

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