Retinal ganglion cell function in recovered optic neuritis: faster is not better

Multiple sclerosis (MS) is a chronic demyelinating disease affecting neurons and their axons at multiple sites in the central nervous system (Peterson et al., 2001, Martinez-Lapiscina et al., 2014). The visual system is highly susceptible to damage from MS (Balcer et al., 2015, Graham and Klistorner, 2017). In fact, optic neuritis (ON) is a common ophthalmological feature in MS patients, which is characterized by loss of visual acuity (VA) and visual field (Chen and Gordon, 2005, Jasse et al., 2013) that generally recover to normal after several months.

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