Impact of 2 generational improvements of colonoscopes on adenoma miss rates: results of a prospective randomized multicenter tandem study

Numerous randomized studies have shown that changing certain features of colonoscopes, usually incorporated when switching from one endoscope generation to the next, mostly do not increase adenoma yield. There is, however, indirect evidence that it may be necessary to skip one instrument generation (ie, changing from one generation to the next but one) to achieve this effect.

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