In reply:

We thank you for your insightful comments with respect to the appropriate treatment and management of opioid withdrawal in the emergency department (ED) setting. We agree with Drs. Flemming and Hoffman in regard to the importance of appropriate referral and follow-up after presentation for acute opioid withdrawal. Given the associated pharmacologic and psychological components of opioid addiction, we believe that this is an important part of the treatment plan that deserves proper attention.

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