Αρχειοθήκη ιστολογίου

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Σάββατο 30 Ιουλίου 2016

Speech and Hearing Disorders,Αισθητική,Cancer,Δερματολογία,Allergy,ΟδοντοΙατρική,Rhinology,Ενδοκρινολογία,Immunology Asthma,Hearing and Balance,Υπνική Άπνοια και Διαταραχές Ύπνου

Υπνική Άπνοια και Διαταραχές Ύπνου
Obstructive sleep apnoea in patients with epilepsy: a meta-analysis
Abstract Purpose The aim of this study was to accurately determine the prevalence of obstructive sleep apnoea (OSA) in patients with epilepsy (PWE) and to evaluate the efficacy of seizure control after treating OSA. Methods Articles were identified through a search of both MEDLINE and Embase. The...

Ενδοκρινολογία
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online
These new articles for The Journal of Clinical Endocrinology & Metabolism are available onlineEarly ReleaseThe Journal of Clinical Endocrinology & Metabolism The Journal of Clinical Endocrinology & Metabolism Home Page...
Ενδοκρινολογία
These new articles for Endocrinology are available online
These new articles for Endocrinology are available onlineEarly ReleaseEndocrinology Endocrinology Home Page Current Issue Past Issues Changes in leptin signaling by SOCS3 modulate...
Allergy Rhinology Immunology Asthma
CD45RA distinguishes CD4+CD25+CD127-/low TSDR demethylated regulatory T cell subpopulations with differential stability and susceptibility to tacrolimus mediated inhibition of suppression.
Background: Adoptive transfer of FOXP3+ regulatory T cells (Treg) offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg expanded ex vivo to remove cellular contaminants requires optimisation. Furthermore,...
Allergy Rhinology Immunology Asthma
An Exciting New Era in Donor Organ Preservation and Transplantation [horizontal ellipsis] Assess, Condition and Repair!
No abstract available from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2al4xtp
Allergy Rhinology Immunology Asthma
Donor-transmitted Atherosclerosis Associated with Worsening Cardiac Allograft Vasculopathy After Heart Transplantation: Serial Volumetric Intravascular Ultrasound Analysis.
Background: The influence of preexisting donor-transmitted atherosclerosis (DA) on cardiac allograft vasculopathy (CAV) development remains unclear. Methods: We performed 3-dimensional intravascular ultrasound (3D-IVUS) analysis in 42 heart transplant (HTx) recipients at 2.1+/-0.9 months (baseline) and...
Allergy Rhinology Immunology Asthma
Increased CD40 ligation and reduced BCR signalling leads to higher IL-10 production in B cells from tolerant kidney transplant patients.
Background: An increased percentage of peripheral transitional B cells producing IL-10 has been observed in patients tolerant to kidney allografts. In healthy volunteers, the balance between the CD40 and B cell receptor (BCR) signalling modulated IL-10 production by B cells, with stimulation via the...
Allergy Rhinology Immunology Asthma
Updated manufacturer and EMA recommendations on the use of mycophenolate acid: balancing the risks for male allograft recipients.
No abstract available from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2akbCqT
Allergy Rhinology Immunology Asthma
Costimulation blockade in kidney transplantation: an update.
In the setting of solid-organ transplantation, calcineurin inhibitor (CNI)-based therapy remains the cornerstone of immunosuppression. However, long-term use of CNIsis associated with some degree of nephrotoxicity. This has led to exploring the blockadeof some costimulation pathways as an efficient immunosuppressive...
Allergy Rhinology Immunology Asthma
Are octogenarians with end stage renal disease candidates for renal transplantation?.
Background: Elderly patients are the fastest growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their eightieth year or older at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation? Methods: Recipients...
Allergy Rhinology Immunology Asthma
Criteria For And Appropriateness Of Renal Transplantation In Elderly Patients With End-Stage Renal Disease: A Literature Review And Position Statement On Behalf Of The European Renal Association-European Dialysis And Transplant Association Descartes Working Group And European Renal Best Practice.
During the last 20 years, waiting lists for renal transplantation (RT) have grown significantly older. However, elderly patients (ie >=65 years of age) are still more rarely referred or accepted to waiting lists and, if enlisted, have less chances of actually receiving a kidney allograft, than younger...
Allergy Rhinology Immunology Asthma
A novel predictor of posttransplant portal hypertension in adult-to-adult living donor liver transplantation: increased estimated spleen/graft volume ratio.
Background: In adult living donor liver transplantation (ALDLT), graft-to-recipient weight ratio (GRWR) of less than 0.8 is incomplete for predicting portal hypertension (>20 mmHg) after reperfusion. We aimed to identify preoperative factors contributing to PVP after reperfusion and to predict portal...
Allergy Rhinology Immunology Asthma
Exploring a role for IL-7 induced homeostatic reconstitution of regulatory T cells post basiliximab therapy: implications for transplantation tolerance.
No abstract available from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2al4PjH
Cancer
In vivo antitumor Activity of a Recombinant IL-7/IL-15
Both IL-7 and IL-15 have become important candidate immunomodulators for cancer treatment. However, IL-7 or IL-15 used alone suffers from shortcomings, such as short serum half-life and limited antitumor effect. We have cloned and expressed a recombinant (r) IL-7/IL-15 fusion protein in which IL-7 and...
Αισθητική Δερματολογία
In vivo antitumor Activity of a Recombinant IL-7/IL-15
Both IL-7 and IL-15 have become important candidate immunomodulators for cancer treatment. However, IL-7 or IL-15 used alone suffers from shortcomings, such as short serum half-life and limited antitumor effect. We have cloned and expressed a recombinant (r) IL-7/IL-15 fusion protein in which IL-7 and...
Κοσμητική ΟδοντοΙατρική
Correlation of cognitive and masticatory function in Alzheimer’s disease
AbstractObjectivesThis study investigated chewing function in elderly individuals with Alzheimer’s disease (AD) and correlated chewing function with cognitive status.Materials and methodsSixteen elderly individuals with mild AD (mean age 76.7 ± 6.3 years; 8 men, 8 women) and 16 age and gender-matched...
Αισθητική Δερματολογία
Assessment of the efficacy and safety of single platelet-rich plasma injection on different types and grades of facial wrinkles
Summary Background Platelet-rich plasma (PRP) is considered as a growing modality for tissue regeneration and a developing research area for clinicians and researchers. PRP injection treatment provides supraphysiological concentrations of growth factors that may help in accelerated tissue remodeling...
Αισθητική Δερματολογία
Nonablative radiofrequency treatment for the skin in the eye area – clinical and cutometrical analysis
Summary Objective The purpose of the research was to evaluate skin elasticity and reduction in the aging eye area after using a nonablative radiofrequency treatment. Material and methods This study included 23 patients, aged 34–58 years with Fitzpatrick skin type II and III. They received...
Αισθητική Δερματολογία
Ten pearls every dermatologist should know about the appropriate use of relaxers
Summary Chemical relaxers are products marketed to straighten the hair and have been principally used by African Americans since the early twentieth century. They contain alkaline agents that break and reform hydrogen and disulfide bonds, leaving hair permanently straightened. Relaxers cause loss...
Cancer
RE: "EVALUATION OF MODERATE ALCOHOL USE WITH QT INTERVAL AND HEART RATE USING MENDELIAN RANDOMIZATION ANALYSIS AMONG OLDER SOUTHERN CHINESE MEN IN THE GUANGZHOU BIOBANK COHORT STUDY"
from #Oncology via alexandrossfakianakis on Inoreader http://ift.tt/2ajbL41 via IFTTT
Αισθητική Δερματολογία
Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2.
Related Articles Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2. Oncoimmunology. 2016 May;5(5):e1100793 Authors: Dabbeche-Bouricha E, Araujo LM, Kato M, Prévost-Blondel A, Garchon HJ...
Cancer
Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2.
Related Articles Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2. Oncoimmunology. 2016 May;5(5):e1100793 Authors: Dabbeche-Bouricha E, Araujo LM, Kato M, Prévost-Blondel A, Garchon HJ...
Αισθητική Δερματολογία
Melanoma driver mutations and immune therapy.
Related Articles Melanoma driver mutations and immune therapy. Oncoimmunology. 2016 May;5(5):e1051299 Authors: Johnson DB, Lovly CM, Sullivan RJ, Carvajal RD, Sosman JA Abstract Melanoma harbors recurrent oncogenic driver mutations in BRAF and NRAS, but these mutations' impact on immunotherapy...
Αισθητική Δερματολογία
Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.
Related Articles Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016 May;5(5):e1114203 Authors: Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile...
Cancer
Melanoma driver mutations and immune therapy.
Related Articles Melanoma driver mutations and immune therapy. Oncoimmunology. 2016 May;5(5):e1051299 Authors: Johnson DB, Lovly CM, Sullivan RJ, Carvajal RD, Sosman JA Abstract Melanoma harbors recurrent oncogenic driver mutations in BRAF and NRAS, but these mutations' impact on immunotherapy...
Cancer
Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.
Related Articles Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016 May;5(5):e1114203 Authors: Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile...
Cancer
Cripto-1 vaccination elicits protective immunity against metastatic melanoma.
Related Articles Cripto-1 vaccination elicits protective immunity against metastatic melanoma. Oncoimmunology. 2016 May;5(5):e1128613 Authors: Ligtenberg MA, Witt K, Galvez-Cancino F, Sette A, Lundqvist A, Lladser A, Kiessling R Abstract Metastatic melanoma is a fatal disease that responds poorly...
Αισθητική Δερματολογία
Cripto-1 vaccination elicits protective immunity against metastatic melanoma.
Related Articles Cripto-1 vaccination elicits protective immunity against metastatic melanoma. Oncoimmunology. 2016 May;5(5):e1128613 Authors: Ligtenberg MA, Witt K, Galvez-Cancino F, Sette A, Lundqvist A, Lladser A, Kiessling R Abstract Metastatic melanoma is a fatal disease that responds poorly...
Cancer
Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting.
Related Articles Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting. Oncoimmunology. 2016 May;5(5):e1136046 Authors: Siurala M, Vähä-Koskela M, Havunen R, Tähtinen S, Bramante...
Cancer
Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients.
Related Articles Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients. Oncoimmunology. 2016 May;5(5):e1137416 Authors: Laheurte C, Galaine J, Beziaud L, Dosset M, Kerzerho J, Jacquemard C, Gaugler B, Ferrand C,...
Αισθητική Δερματολογία
Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting.
Related Articles Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting. Oncoimmunology. 2016 May;5(5):e1136046 Authors: Siurala M, Vähä-Koskela M, Havunen R, Tähtinen S, Bramante...
Αισθητική Δερματολογία
Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients.
Related Articles Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients. Oncoimmunology. 2016 May;5(5):e1137416 Authors: Laheurte C, Galaine J, Beziaud L, Dosset M, Kerzerho J, Jacquemard C, Gaugler B, Ferrand C,...
Cancer
Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma.
Related Articles Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma. Oncoimmunology. 2016 May;5(5):e1143997 Authors: Karydis I, Chan PY, Wheater M, Arriola E, Szlosarek PW, Ottensmeier CH Abstract Background: Untreated metastatic uveal melanoma...
Αισθητική Δερματολογία
Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma.
Related Articles Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma. Oncoimmunology. 2016 May;5(5):e1143997 Authors: Karydis I, Chan PY, Wheater M, Arriola E, Szlosarek PW, Ottensmeier CH Abstract Background: Untreated metastatic uveal melanoma...
Hearing and Balance
PAP Alert - Otology & Neurotology
Published Ahead-of-Print The following 12 items were added to...
Αισθητική Δερματολογία
Fractal and multifractal analysis of PET/CT images of metastatic melanoma before and after treatment with ipilimumab
Abstract Background PET/CT with F-18-fluorodeoxyglucose (FDG) images of patients suffering from metastatic melanoma have been analysed using fractal and multifractal analysis to assess the impact of monoclonal antibody ipilimumab treatment with respect to therapy outcome. Results Thirty-one cases...
Cancer
Fractal and multifractal analysis of PET/CT images of metastatic melanoma before and after treatment with ipilimumab
Abstract Background PET/CT with F-18-fluorodeoxyglucose (FDG) images of patients suffering from metastatic melanoma have been analysed using fractal and multifractal analysis to assess the impact of monoclonal antibody ipilimumab treatment with respect to therapy outcome. Results Thirty-one cases...
Ενδοκρινολογία
Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: a 2016 position statement of the Italian Society of Endocrinology and the Italian Thyroid Association
Abstract Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired...
Ενδοκρινολογία
New markers of insulin resistance in polycystic ovary syndrome
Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine-metabolic disorder in women of reproductive age. The diagnostic criteria include two out of three features: hyperandrogenism, polycystic ovaries on ultrasound and menstrual irregularities (Rotterdam Criteria 2003). PCOS patients...
Ενδοκρινολογία
Evaluation of a novel tablet application for improvement in colonoscopy training and mentoring (with video)
Endoscopic training can be challenging for the trainee and preceptor. Frustration can result from ineffective communication regarding areas of interest. Our team developed a novel tablet application for real-time mirroring of the colonoscopy examination that allows preceptors to make annotations directly...
Ενδοκρινολογία
Maneuverability and safety of magnetic-controlled capsule endoscopy system to examine the human colon under real-time monitoring by colonoscopy: a pilot study
Colon capsule endoscopy (CCE) has become an alternative method to evaluate the colonic mucosa without pain, sedation, and gas insufflation in recent years. The magnetic-controlled capsule endoscopy (MCCE) system is an innovative ingestible colon capsule. We performed a pilot study to assess its maneuverability...
Speech and Hearing Disorders
Protective Effect of Astaxanthin on Vocal Fold Injury and Inflammation Due to Vocal Loading: A Clinical Trial
Professional voice users, such as singers and teachers, are at greater risk of developing vocal fold injury from excessive use of voice; thus, protection of the vocal fold is essential. One of the most important factors that aggravates injury is the production of reactive oxygen species at the wound...
Speech and Hearing Disorders
Objective Identification of Prepubertal Female Singers and Non-singers by Singing Power Ratio Using Matlab
The field of music is increasingly gaining scope and attracting researchers from varied fields in terms of improvising the art of voice modulation in singing. There has been a lot of competition, and young budding singers are emerging with more talent. This study is aimed to develop software to differentiate...
Αισθητική Δερματολογία
Onychomadèse et syndrome pieds-mains-bouche
Publication date: Available online 29 July 2016Source:Annales de Dermatologie et de Vénéréologie Author(s): D. Haidar, V. Boulanger-Azam, A. Dompmartin from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/2akd1yU via IFTTT
Αισθητική Δερματολογία
5 Utility of Whole Genome SNP Microarray and Targeted Somatic Mutations in Evaluation of Melanoma, Histologic Mimics of Melanoma, and Glioblastoma
Publication date: June 2016Source:Cancer Genetics, Volume 209, Issue 6 Author(s): Alka Chaubey, Ashis Mondal, WonSok Lee, Amyn Rojiani, Barbara DuPont, Ravindra Kolhe http://ift.tt/2akqdFU
Cancer
5 Utility of Whole Genome SNP Microarray and Targeted Somatic Mutations in Evaluation of Melanoma, Histologic Mimics of Melanoma, and Glioblastoma
Publication date: June 2016Source:Cancer Genetics, Volume 209, Issue 6 Author(s): Alka Chaubey, Ashis Mondal, WonSok Lee, Amyn Rojiani, Barbara DuPont, Ravindra Kolhe http://ift.tt/2akqdFU
Allergy Rhinology Immunology Asthma
Hypersensitivity Pneumonitis Due to Metalworking Fluid Aerosols
Abstract Purpose of Review This review summarises the clinical knowledge of hypersensitivity pneumonitis in workers exposed to aerosols of metalworking fluid, reviewing published outbreaks and clinical cases. Recent Findings Metalworking fluid exposure has become the commonest recognised cause of...
Cancer
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Allergy Rhinology Immunology Asthma
Patient engagement and patient support programs in allergy immunotherapy: a call to action for improving long-term adherence
Allergy immunotherapy (AIT) is acknowledged to produce beneficial mid- and long-term clinical and immunologic effects and increased quality of life in patients with allergic respiratory diseases (such as aller... from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2aknD2z
Αισθητική Δερματολογία
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Cancer
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Αισθητική Δερματολογία
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Allergy Rhinology Immunology Asthma
Beta-glucan contamination of pharmaceutical products: How much should we accept?
Abstract Beta-glucans are large polysaccharides produced by a range of prokaryotic and eukaryotic organisms. They have potential immunostimulatory properties and have been used with therapeutic intent as anti-microbial and anti-tumour agents. A range of other potentially beneficial effects have been...
Αισθητική Δερματολογία
Terbinafin
Zusammenfassung Das Allylamin Terbinafin ist das in Deutschland wohl am häufigsten verordnete systemische Antimykotikum zur Behandlung von Dermato- und Onychomykosen. Zugelassen für Patienten ab 18 Jahren, wird Terbinafin jedoch entsprechend Arzneimittelgesetz als individueller Heilversuch immer mehr...
Αισθητική Δερματολογία
Coffee consumption and the risk of malignant melanoma in the Norwegian Women and Cancer (NOWAC) Study
Abstract Background Coffee contains biologically-active substances that suppress carcinogenesis in vivo, and coffee consumption has been associated with a lower risk of malignant melanoma. We studied the impact of total coffee consumption and of different brewing methods on the incidence of malignant...
Αισθητική Δερματολογία
The Patient’s Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy
Abstract Background The Goeckerman regimen remains one of the oldest, most reliable treatment options for patients with moderate to severe psoriasis. Goeckerman therapy currently consists of exposure to ultraviolet B light and application of crude coal tar. The details of the procedure can be confusing...
Cancer
Coffee consumption and the risk of malignant melanoma in the Norwegian Women and Cancer (NOWAC) Study
Abstract Background Coffee contains biologically-active substances that suppress carcinogenesis in vivo, and coffee consumption has been associated with a lower risk of malignant melanoma. We studied the impact of total coffee consumption and of different brewing methods on the incidence of malignant...
Allergy Rhinology Immunology Asthma
Hypersensitivity Pneumonitis Due to Metalworking Fluid Aerosols
Abstract Purpose of Review This review summarises the clinical knowledge of hypersensitivity pneumonitis in workers exposed to aerosols of metalworking fluid, reviewing published outbreaks and clinical cases. Recent Findings Metalworking fluid exposure has become the commonest recognised cause of...
Αισθητική Δερματολογία
The Patient’s Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy
Abstract Background PUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of PUVA. Studies have shown that patients...
Αισθητική Δερματολογία
The Patient’s Guide to Psoriasis Treatment. Part 1: UVB Phototherapy
Abstract Background Psoriasis is a chronic immune-mediated disease that affects 2–3% of the world population. Ultraviolet B (UVB) phototherapy is an effective treatment for psoriasis compared to other systemic treatments. Currently there is a lack of easily accessible online patient educational material...
Αισθητική Δερματολογία
The Patient’s Guide to Psoriasis Treatment. Part 3: Biologic Injectables
Abstract Background An increasing number of injectable biologics are now available for the treatment of psoriasis. However, for individuals who have never received this therapy, the process of performing a self-injection can be daunting. There is lack of patient educational material on how to perform...
Αισθητική Δερματολογία
Dimethylfumarate inhibits melanoma cell proliferation via p21 and p53 induction and bcl-2 and cyclin B1 downregulation
Abstract Recent evidence suggests that dimethylfumarate (DMF), known as a highly potent anti-psoriatic agent, might have anti-tumorigenic properties in melanoma. It has recently been demonstrated that DMF inhibits melanoma proliferation by apoptosis and cell cycle inhibition and therefore inhibits melanoma...
Cancer
Dimethylfumarate inhibits melanoma cell proliferation via p21 and p53 induction and bcl-2 and cyclin B1 downregulation
Abstract Recent evidence suggests that dimethylfumarate (DMF), known as a highly potent anti-psoriatic agent, might have anti-tumorigenic properties in melanoma. It has recently been demonstrated that DMF inhibits melanoma proliferation by apoptosis and cell cycle inhibition and therefore inhibits melanoma...
Αισθητική Δερματολογία
Vitamin D: A New Intervention for Melanoma?
Does the association of low vitamin D levels and poor outcomes in melanoma patients point to supplementation as a potential intervention for melanoma?Medscape Oncology http://ift.tt/2aCpDps
Cancer
Vitamin D: A New Intervention for Melanoma?
Does the association of low vitamin D levels and poor outcomes in melanoma patients point to supplementation as a potential intervention for melanoma?Medscape Oncology http://ift.tt/2aCpDps
Allergy Rhinology Immunology Asthma
House dust mite sublingual tablet is effective and safe in patients with allergic rhinitis
Abstract Background House dust mite (HDM) is the major indoor allergen for allergic diseases such as allergic rhinitis (AR) and asthma. Although sublingual immunotherapy (SLIT) is a curative treatment for HDM-induced AR, data from large-scale studies are limited. We evaluated the efficacy and...
Allergy Rhinology Immunology Asthma
Crossing the threshold: can outcome data from food challenges be used to predict risk of anaphylaxis in the community?
Abstract There is increasing interest in using data from oral food challenges (OFC) performed under medical supervision to assist in allergy risk management, both in industry (allergen risk management) (1) and in the clinical management of the allergic individual (2). Data relating to the minimum...
Hearing and Balance
You Too Could Record the Earth
We have recently talked about making soundscapes from photographs and a group of professional recording artists joining forces to document the exquisite sounds of nature. The real world, no doubt, is much more sonically diverse and full. Is there a way to capture the characteristic sounds of the...
Ενδοκρινολογία
Risk of Infection Transmission in Curvilinear Array Echoendoscopes: Results of a Prospective Reprocessing and Culture Registry
The complex design of the elevator mechanism in duodenoscopes has been recognized as a challenge for disinfection and recently implicated as a potential source of persistent bacterial contamination. Curvilinear array (CLA) echoendoscopes also have an elevator mechanism, however there are no recommendations...
Κοσμητική ΟδοντοΙατρική
Evaluation of three analysis methods for 99mTc MDP SPECT scintigraphy in the diagnosis of unilateral condylar hyperplasia
Publication date: Available online 28 July 2016Source:International Journal of Oral and Maxillofacial SurgeryAuthor(s): H. Rushinek, R. Tabib, Y. Fleissig, M. Klein, S. TshoriThe aims of the study were to evaluate the diagnostic accuracy and utility of the mean region of interest (ROI) and mean and maximum...
Allergy Rhinology Immunology Asthma
Skin provocation tests may help to diagnose atopic dermatitis
Abstract Background Atopic dermatitis (AD) is a common skin disorder. Its diagnosis relies on clinical judgment. Mild and untypical manifestations may cause diagnostic difficulties. Biomarkers for the differential diagnostic work up of AD are needed. Objective To test if the results...
Hearing and Balance
Sound localization in the presence of multiple reflections using a binaurally integrated cross-correlation/auto-correlation mechanism
A precedence effect model is described that can use a binaural signal to robustly localize a sound source in the presence of multiple reflections for the frontal horizontal plane. The model also estimates a room impulse response from a running binaural signal and determines the spatial locations and...
Αισθητική Δερματολογία
Metastatic Ocular Melanoma to the Liver Exhibits Infiltrative and Nodular Growth Patterns
We examined liver specimens from 15 patients with uveal melanoma (UM) who had succumbed to their disseminated disease. We found two distinct growth patterns of UM metastasis: infiltrative (n=12) and nodular (n=3). In the infiltrative pattern, individual UM cells with a CD133+ cancer stem cell-like phenotype...
Cancer
Metastatic Ocular Melanoma to the Liver Exhibits Infiltrative and Nodular Growth Patterns
We examined liver specimens from 15 patients with uveal melanoma (UM) who had succumbed to their disseminated disease. We found two distinct growth patterns of UM metastasis: infiltrative (n=12) and nodular (n=3). In the infiltrative pattern, individual UM cells with a CD133+ cancer stem cell-like phenotype...
Cancer
Pregnancy complicated by haemorrhagic ascites in a woman with newly diagnosed HIV
A young pregnant Zambian woman was referred from a district hospital in South Zambia to the university teaching hospital, Lusaka with severe anaemia and ascites. The ascites had developed over a month and the woman was currently 15 weeks pregnant. Further workup revealed that the patient was HIV-positive...
Cancer
Migration of peripherally inserted central catheter likely into the azygos vein: a conservative management
Description A 31-year-old female patient with systolic heart failure (ejection fraction of 30%) and automatic implantable cardioverter-defibrillator (AICD) was admitted to the hospital with sepsis from Staphylococcus hominis and Staphylococcus capitis bacteraemia. A transesophageal echocardiogram...
Cancer
Calcific tendinitis of biceps femoris: an unusual site and cause for lateral knee pain
A 37-year-old man presented to the acute knee and sports medicine clinic with atraumatic lateral knee pain. He had point tenderness over the lateral aspect of his knee which had not settled with anti-inflammatory medications. Imaging revealed a large opaque lesion lateral to the knee and although there...
Allergy Rhinology Immunology Asthma
Scombroid syndrome: it seems to be fish allergy but... it isn't.
Purpose of review: Scombroid poisoning is a frequent cause of admission in emergency department. In everyday clinical practice, it can be difficult to discriminate between scombroid syndrome and fish allergy. The aim of this review is to provide the clinician some instruments to make a correct differential...
Allergy Rhinology Immunology Asthma
Regulation of the host immune system by helminth parasites
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Rick M. Maizels, Henry J. McSorley Helminth parasite infections are associated with a battery of immunomodulatory mechanisms, which impact all facets of the host immune response to ensure their...
Allergy Rhinology Immunology Asthma
Timely follow-up of a GATA2 deficiency patient allows successful treatment
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Sara Ciullini Mannurita, Marina Vignoli, Gloria Colarusso, Fabio Tucci, Marinella Veltroni, Stefano Frenos, Veronica Tintori, Maurizio Aricò, Venetia Bigley, Matthew Collin, Claudio Favre, Eleonora...
Allergy Rhinology Immunology Asthma
Defective NK cell activity in a mouse model of eczema herpeticum
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Yuko Kawakami, Tomoaki Ando, Jong-Rok Lee, Gisen Kim, Yu Kawakami, Tae Nakasaki, Manando Nakasaki, Kenji Matsumoto, Youn Soo Choi, Toshiaki Kawakami BackgroundPatients with atopic dermatitis...
Hearing and Balance
Concurrent validity and reliability of using ground reaction force and center of pressure parameters in the determination of leg movement initiation during single leg lift
Publication date: Available online 29 July 2016Source:Gait & Posture Author(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie Bussey Postural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means...
Hearing and Balance
Concurrent validity and reliability of using ground reaction force and center of pressure parameters in the determination of leg movement initiation during single leg lift
Publication date: Available online 29 July 2016Source:Gait & Posture Author(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie Bussey Postural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means...
Αισθητική Δερματολογία
Ability of sodium copper chlorophyllin complex to repair photoaged skin by stimulation of biomarkers in human extracellular matrix
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/2aChbpM via IFTTT
Speech and Hearing Disorders
The Effectiveness of Pitch-raising Surgery in Male-to-Female Transsexuals: A Systematic Review
This study aimed to review the evidence of the effectiveness of pitch-raising surgery performed in male-to-female transsexuals.from Speech via xlomafota13 on Inoreader http://ift.tt/2ahfS0a
Speech and Hearing Disorders
Identifying Treatment Response of Sertraline in a Teenager with Selective Mutism using Electrophysiological Neuroimaging.
Identifying Treatment Response of Sertraline in a Teenager with Selective Mutism using Electrophysiological Neuroimaging.Int J Clin Pharmacol Toxicol. 2016 Jun;5(4):216-219Authors: Eugene AR, Masiak JAbstractBACKGROUND: Selective Mutism is described as the inability to verbally express oneself in anxiety...
Speech and Hearing Disorders
MHealth to Improve Measles Immunization in Guinea-Bissau: Study Protocol for a Randomized Controlled Trial.
MHealth to Improve Measles Immunization in Guinea-Bissau: Study Protocol for a Randomized Controlled Trial.JMIR Res Protoc. 2016;5(3):e158Authors: Rossing E, Ravn H, Batista CS, Rodrigues AAbstractBACKGROUND: Recent studies have revealed a low measles vaccination (MV) rate in the Republic of Guinea-Bissau...
Speech and Hearing Disorders
An unusual cause of hoarseness and recurrent laryngeal nerve palsy.
An unusual cause of hoarseness and recurrent laryngeal nerve palsy.JAAPA. 2016 Aug;29(8):35-37Authors: Truong P, Dickerson LAbstractRecurrent laryngeal nerve palsy and thyroid disease suggest locally invasive thyroid malignancy. In contrast, recurrent laryngeal nerve palsy caused by benign multinodular...
Speech and Hearing Disorders
'Festival in a Box': Development and qualitative evaluation of an outreach programme to engage socially isolated people with dementia.
'Festival in a Box': Development and qualitative evaluation of an outreach programme to engage socially isolated people with dementia.Dementia (London). 2016 Jul 27;Authors: Eades M, Lord K, Cooper CAbstractWe co-designed and piloted 'Festival in a Box', an outreach programme to enable socially isolated...
Speech and Hearing Disorders
In Setting Global Policy, Nursing's Voice Is Needed.
In Setting Global Policy, Nursing's Voice Is Needed.Am J Nurs. 2016 Aug;116(8):7Authors: Shamian JAbstractIt's time to reach beyond the bedside.PMID: 27466900 [PubMed - as supplied by publisher]from Speech via xlomafota13 on Inoreader http://ift.tt/2ajbECz
Speech and Hearing Disorders
An exploratory investigation of the daily talk time of people with non-fluent aphasia and non-aphasic peers
10.1080/17549507.2016.1209558<br/>Caitlin Brandenburgfrom Speech via xlomafota13 on Inoreader http://ift.tt/2ajaNSt
Speech and Hearing Disorders
Service utilisation and costs of language impairment in children: The early language in Victoria Australian population-based study
10.1080/17549507.2016.1209559<br/>HA N. D. Lefrom Speech via xlomafota13 on Inoreader http://ift.tt/2aigr40
Speech and Hearing Disorders
Expanding phenotype of p.Ala140Val mutation in MECP2 in a 4 generation family with X-linked intellectual disability and spasticity.
Expanding phenotype of p.Ala140Val mutation in MECP2 in a 4 generation family with X-linked intellectual disability and spasticity.Eur J Med Genet. 2016 Jul 24;Authors: Lambert S, Maystadt I, Boulanger S, Vrielynck P, Destrée A, Lederer D, Moortgat SAbstractMutations in MECP2 (MIM #312750), located on...
Speech and Hearing Disorders
Impact of pneumococcal conjugate vaccine on pediatric tympanostomy tube insertion in partial immunized population.
Related ArticlesImpact of pneumococcal conjugate vaccine on pediatric tympanostomy tube insertion in partial immunized population.ScientificWorldJournal. 2015;2015:248678Authors: Wang MC, Wang YP, Chu CH, Tu TY, Shiao AS, Chou PAbstractOBJECTIVE: To investigate the impact of seven-valent pneumococcal...
Speech and Hearing Disorders
Service utilisation and costs of language impairment in children: The early language in Victoria Australian population-based study.
Service utilisation and costs of language impairment in children: The early language in Victoria Australian population-based study.Int J Speech Lang Pathol. 2016 Jul 28;:1-10Authors: Le HN, Gold L, Mensah F, Eadie P, Bavin EL, Bretherton L, Reilly SAbstractPURPOSE: To examine (1) the patterns of service...
Speech and Hearing Disorders
Magnetoencephalography shows atypical sensitivity to linguistic sound sequences in autism spectrum disorder.
Magnetoencephalography shows atypical sensitivity to linguistic sound sequences in autism spectrum disorder.Neuroreport. 2016 Jul 27;Authors: Brennan JR, Wagley N, Kovelman I, Bowyer SM, Richard AE, Lajiness-O'Neill RAbstractNeuroscientific evidence points toward atypical auditory processing in individuals...
Speech and Hearing Disorders
Conversational topics discussed by individuals with severe traumatic brain injury and their communication partners during sub-acute recovery.
Conversational topics discussed by individuals with severe traumatic brain injury and their communication partners during sub-acute recovery.Brain Inj. 2016 Jul 28;:1-14Authors: Brassel S, Kenny B, Power E, Elbourn E, McDonald S, Tate R, MacWhinney B, Turkstra L, Holland A, Togher LAbstractPRIMARY OBJECTIVE:...
Speech and Hearing Disorders
A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.
A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.Hum Mol Genet. 2016 Jul 27;Authors: Baroncelli L, Molinaro A, Cacciante F, Alessandrì MG, Napoli D, Putignano E, Tola J, Leuzzi V, Cioni G, Pizzorusso TAbstractMutations...
Speech and Hearing Disorders
Neural correlates of second-language communication and the effect of language anxiety.
Neural correlates of second-language communication and the effect of language anxiety.Neuropsychologia. 2016 Apr;84:e2-12Authors: Jeong H, Sugiura M, Suzuki W, Sassa Y, Hashizume H, Kawashima RAbstractCommunicative speech is a type of language use that involves goal-directed action targeted at another...
Speech and Hearing Disorders
Care of patients with permanent tracheostomy.
Related ArticlesCare of patients with permanent tracheostomy.Nurs Times. 2016 May 25-Jun 14;112(21-23):20-2Authors: Everitt EAbstractThe third article in our series on tracheostomy care discusses the care of patients with a permanent tracheostomy. While these patients make up a small proportion of all...
Speech and Hearing Disorders
Hearing and vision screening tools for long-term care residents with dementia: protocol for a scoping review.
Hearing and vision screening tools for long-term care residents with dementia: protocol for a scoping review.BMJ Open. 2016;6(7):e011945Authors: McGilton KS, Höbler F, Campos J, Dupuis K, Labreche T, Guthrie DM, Jarry J, Singh G, Wittich WAbstractINTRODUCTION: Hearing and vision loss among long-term...

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