10:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: Available online 29 July 2016Source:Microbes and Infection Author(s): Mateja Ozanic, Valentina Marecic, Marie Lindgren, Anders Sjöstedt, Marina Santic Several bacterial pathogens interact with their host through protein secretion effectuated by a type VI secretion system (T6SS)....
10:51
OtoRhinoLaryngology Now by Alexandros G. Sfakianakis
Ribosome-inactivating proteins have been isolated from Trichosanthes kirilowii root tubers and seeds, including trichosanthin, karasurin and T 33 from root tubers and trichosanthrip, trichokirin, alpha-kirilowin, beta-kirilowin and trichoanguin from seeds. The aforementioned proteins show structural...
10:51
OtoRhinoLaryngology Now by Alexandros G. Sfakianakis
It is high time now to discover novel drugs due to the increasing rate of drug resistance by the pathogen organisms and target cells as well as the dependence or tolerance of the body towards the drug. As it is obvious that significant numbers of the modern day pharmaceuticals are derived from natural...
10:51
OtoRhinoLaryngology Now by Alexandros G. Sfakianakis
Purpose of review: Perforator flaps are increasingly being used to reconstruct head and neck defects. They offer several advantages over nonperforator-based flaps with lower donor site morbidity and a versatile range of reconstructive options. The anterolateral thigh flap is well established in the head...
10:51
OtoRhinoLaryngology Now by Alexandros G. Sfakianakis
This study aimed to determine the radiation dose of temporal bone computed tomography (TBCT) to detect pediatric congenital cholesteatoma (CC), and suggests strategy for lowering perioperative radiation dose. http://ift.tt/2aDnSFm
10:51
OtoRhinoLaryngology Now by Alexandros G. Sfakianakis
This study aimed to review the evidence of the effectiveness of pitch-raising surgery performed in male-to-female transsexuals. http://ift.tt/2ahfS0a
10:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Abstract Objectives This study investigated chewing function in elderly individuals with Alzheimer's disease (AD) and correlated chewing function with cognitive status. Materials and methods Sixteen elderly individuals with mild AD (mean age 76.7 ± 6.3 years; 8 men, 8 women) and 16 age and gender-matched...
10:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2a8EoMI via IFTTT
10:37
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2a8EoMI
10:34
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Abstract Objectives This study investigated chewing function in elderly individuals with Alzheimer's disease (AD) and correlated chewing function with cognitive status. Materials and methods Sixteen elderly individuals with mild AD (mean age 76.7 ± 6.3 years; 8 men, 8 women) and 16 age and gender-matched...
10:23
Head and Neck Cancers by Alexandros G. Sfakianakis
Abstract Objectives This study investigated chewing function in elderly individuals with Alzheimer's disease (AD) and correlated chewing function with cognitive status. Materials and methods Sixteen elderly individuals with mild AD (mean age 76.7 ± 6.3 years; 8 men, 8 women) and 16 age and gender-matched...
09:59
OtoRhinoLaryngology - Head and Neck Surgery
No abstract availablehttp://ift.tt/2al6pSR
09:59
OtoRhinoLaryngology - Head and Neck Surgery
Purpose of review: Perforator flaps are increasingly being used to reconstruct head and neck defects. They offer several advantages over nonperforator-based flaps with lower donor site morbidity and a versatile range of reconstructive options. The anterolateral thigh flap is well established in the head...
09:55
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al6pSR via IFTTT
09:55
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Purpose of review: Perforator flaps are increasingly being used to reconstruct head and neck defects. They offer several advantages over nonperforator-based flaps with lower donor site morbidity and a versatile range of reconstructive options. The anterolateral thigh flap is well established in the head...
09:55
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al6pSR via IFTTT
09:52
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2al6pSR
09:52
Head and Neck Cancers by Alexandros G. Sfakianakis
Purpose of review: Perforator flaps are increasingly being used to reconstruct head and neck defects. They offer several advantages over nonperforator-based flaps with lower donor site morbidity and a versatile range of reconstructive options. The anterolateral thigh flap is well established in the head...
09:48
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Purpose of review: Perforator flaps are increasingly being used to reconstruct head and neck defects. They offer several advantages over nonperforator-based flaps with lower donor site morbidity and a versatile range of reconstructive options. The anterolateral thigh flap is well established in the head...
09:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: Adoptive transfer of FOXP3+ regulatory T cells (Treg) offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg expanded ex vivo to remove cellular contaminants requires optimisation. Furthermore,...
09:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al4xtp via IFTTT
09:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: The influence of preexisting donor-transmitted atherosclerosis (DA) on cardiac allograft vasculopathy (CAV) development remains unclear. Methods: We performed 3-dimensional intravascular ultrasound (3D-IVUS) analysis in 42 heart transplant (HTx) recipients at 2.1+/-0.9 months (baseline) and...
09:41
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: An increased percentage of peripheral transitional B cells producing IL-10 has been observed in patients tolerant to kidney allografts. In healthy volunteers, the balance between the CD40 and B cell receptor (BCR) signalling modulated IL-10 production by B cells, with stimulation via the...
09:40
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2akbCqT via IFTTT
09:40
OtoRhinoLaryngology by Alexandros G.Sfakianakis
In the setting of solid-organ transplantation, calcineurin inhibitor (CNI)-based therapy remains the cornerstone of immunosuppression. However, long-term use of CNIsis associated with some degree of nephrotoxicity. This has led to exploring the blockadeof some costimulation pathways as an efficient immunosuppressive...
09:40
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: Elderly patients are the fastest growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their eightieth year or older at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation? Methods: Recipients...
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
Publication date: December 2016Source:Current Opinion in Neurobiology, Volume 41 Author(s): Zhenyu Liu, Ali S Hamodi, Kara G Pratt The retinotectal circuit is the major component of the amphibian visual system. It is comprised of the retinal ganglion cells (RGCs) in the eye, which project their axons...
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2aDy8ki
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2aDxEL6
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2aFuDGW
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
Intracranial pressure (ICP) is the pressure inside the bony calvarium and can be affected by a variety of processes, such as intracranial masses and edema, obstruction or leakage of cerebrospinal fluid, and obstruction of venous outflow. This review focuses on the imaging of 2 important but less well...
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
No abstract available http://ift.tt/2aDxFi8
09:37
Head and Neck Cancers by Alexandros G. Sfakianakis
BACKGROUND: Embolic protection devices are used during carotid artery stenting procedures to reduce risk of distal embolization. Although this is a standard procedural recommendation, no studies have shown superiority of these devices over unprotected stenting procedures. OBJECTIVE: To assess the periprocedural...
09:33
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: Adoptive transfer of FOXP3+ regulatory T cells (Treg) offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg expanded ex vivo to remove cellular contaminants requires optimisation. Furthermore,...
09:33
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al4xtp via IFTTT
09:33
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: The influence of preexisting donor-transmitted atherosclerosis (DA) on cardiac allograft vasculopathy (CAV) development remains unclear. Methods: We performed 3-dimensional intravascular ultrasound (3D-IVUS) analysis in 42 heart transplant (HTx) recipients at 2.1+/-0.9 months (baseline) and...
09:33
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: An increased percentage of peripheral transitional B cells producing IL-10 has been observed in patients tolerant to kidney allografts. In healthy volunteers, the balance between the CD40 and B cell receptor (BCR) signalling modulated IL-10 production by B cells, with stimulation via the...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2akbCqT via IFTTT
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
In the setting of solid-organ transplantation, calcineurin inhibitor (CNI)-based therapy remains the cornerstone of immunosuppression. However, long-term use of CNIsis associated with some degree of nephrotoxicity. This has led to exploring the blockadeof some costimulation pathways as an efficient immunosuppressive...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: Elderly patients are the fastest growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their eightieth year or older at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation? Methods: Recipients...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
During the last 20 years, waiting lists for renal transplantation (RT) have grown significantly older. However, elderly patients (ie >=65 years of age) are still more rarely referred or accepted to waiting lists and, if enlisted, have less chances of actually receiving a kidney allograft, than younger...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: In adult living donor liver transplantation (ALDLT), graft-to-recipient weight ratio (GRWR) of less than 0.8 is incomplete for predicting portal hypertension (>20 mmHg) after reperfusion. We aimed to identify preoperative factors contributing to PVP after reperfusion and to predict portal...
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al4PjH via IFTTT
09:32
OtoRhinoLaryngology by Alexandros G.Sfakianakis
During the last 20 years, waiting lists for renal transplantation (RT) have grown significantly older. However, elderly patients (ie >=65 years of age) are still more rarely referred or accepted to waiting lists and, if enlisted, have less chances of actually receiving a kidney allograft, than younger...
09:26
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Background: In adult living donor liver transplantation (ALDLT), graft-to-recipient weight ratio (GRWR) of less than 0.8 is incomplete for predicting portal hypertension (>20 mmHg) after reperfusion. We aimed to identify preoperative factors contributing to PVP after reperfusion and to predict portal...
09:26
OtoRhinoLaryngology by Alexandros G.Sfakianakis
No abstract available from #ENT via xlomafota13 on Inoreader http://ift.tt/2al4PjH via IFTTT
08:42
Melanoma by Alexandros G. Sfakianakis
Both IL-7 and IL-15 have become important candidate immunomodulators for cancer treatment. However, IL-7 or IL-15 used alone suffers from shortcomings, such as short serum half-life and limited antitumor effect. We have cloned and expressed a recombinant (r) IL-7/IL-15 fusion protein in which IL-7 and...
08:28
OtoRhinoLaryngology - Head and Neck Surgery
Ribosome-inactivating proteins have been isolated from Trichosanthes kirilowii root tubers and seeds, including trichosanthin, karasurin and T 33 from root tubers and trichosanthrip, trichokirin, alpha-kirilowin, beta-kirilowin and trichoanguin from seeds. The aforementioned proteins show structural...
08:28
OtoRhinoLaryngology - Head and Neck Surgery
It is high time now to discover novel drugs due to the increasing rate of drug resistance by the pathogen organisms and target cells as well as the dependence or tolerance of the body towards the drug. As it is obvious that significant numbers of the modern day pharmaceuticals are derived from natural...
07:42
Thyroid Disorders by Alexandros G.Sfakianakis
Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare but emerging renal neoplasm that morphologically mimics follicular carcinoma of the thyroid but lacks immunohistochemical expression of thyroid markers such as TTF-1 and thyroglobulin. Here, a case of an incidentally discovered TLFCK in...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2. Oncoimmunology. 2016 May;5(5):e1100793 Authors: Dabbeche-Bouricha E, Araujo LM, Kato M, Prévost-Blondel A, Garchon HJ...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Melanoma driver mutations and immune therapy. Oncoimmunology. 2016 May;5(5):e1051299 Authors: Johnson DB, Lovly CM, Sullivan RJ, Carvajal RD, Sosman JA Abstract Melanoma harbors recurrent oncogenic driver mutations in BRAF and NRAS, but these mutations' impact on immunotherapy...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016 May;5(5):e1114203 Authors: Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Cripto-1 vaccination elicits protective immunity against metastatic melanoma. Oncoimmunology. 2016 May;5(5):e1128613 Authors: Ligtenberg MA, Witt K, Galvez-Cancino F, Sette A, Lundqvist A, Lladser A, Kiessling R Abstract Metastatic melanoma is a fatal disease that responds poorly...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting. Oncoimmunology. 2016 May;5(5):e1136046 Authors: Siurala M, Vähä-Koskela M, Havunen R, Tähtinen S, Bramante...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients. Oncoimmunology. 2016 May;5(5):e1137416 Authors: Laheurte C, Galaine J, Beziaud L, Dosset M, Kerzerho J, Jacquemard C, Gaugler B, Ferrand C,...
04:59
Melanoma by Alexandros G. Sfakianakis
Related Articles Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma. Oncoimmunology. 2016 May;5(5):e1143997 Authors: Karydis I, Chan PY, Wheater M, Arriola E, Szlosarek PW, Ottensmeier CH Abstract Background: Untreated metastatic uveal melanoma...
02:44
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Professional voice users, such as singers and teachers, are at greater risk of developing vocal fold injury from excessive use of voice; thus, protection of the vocal fold is essential. One of the most important factors that aggravates injury is the production of reactive oxygen species at the wound...
02:13
Thyroid Disorders by Alexandros G.Sfakianakis
Objective: The aim of this study was to confirm the equivalent efficacy of recombinant human TSH (rhTSH) and thyroid hormone withdrawal (THW) as used in the preparation for low-dose and high-dose radioactive iodine (RAI) ablation in Korean patients with differentiated thyroid carcinoma. Subjects and...
02:13
Thyroid Disorders by Alexandros G.Sfakianakis
Abstract Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired...
01:59
Melanoma by Alexandros G. Sfakianakis
Abstract Background PET/CT with F-18-fluorodeoxyglucose (FDG) images of patients suffering from metastatic melanoma have been analysed using fractal and multifractal analysis to assess the impact of monoclonal antibody ipilimumab treatment with respect to therapy outcome. Results Thirty-one cases...
01:56
OtoRhinoLaryngology - Head and Neck Surgery
The rehabilitation of edentulous atrophic mandibles with dental implants is often threatened where there has been loss of horizontal alveolar bone. Techniques to augment the bone include guided bony regeneration, distraction osteogenesis, ridge splitting osteotomy, onlay grafting with block grafts (autologous...
01:26
OtoRhinoLaryngology - Head and Neck Surgery
Professional voice users, such as singers and teachers, are at greater risk of developing vocal fold injury from excessive use of voice; thus, protection of the vocal fold is essential. One of the most important factors that aggravates injury is the production of reactive oxygen species at the wound...
01:26
OtoRhinoLaryngology - Head and Neck Surgery
The field of music is increasingly gaining scope and attracting researchers from varied fields in terms of improvising the art of voice modulation in singing. There has been a lot of competition, and young budding singers are emerging with more talent. This study is aimed to develop software to differentiate...
01:26
OtoRhinoLaryngology - Head and Neck Surgery
Thank you for giving us the chance to reply to the Letter to the Editor critiquing certain aspects of our article “Does the piezoelectric surgical technique produce fewer postoperative sequelae after lower third molar surgery than conventional rotary instruments? A systematic review and meta-analysis”.1...
01:26
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Purpose of Review This review summarises the clinical knowledge of hypersensitivity pneumonitis in workers exposed to aerosols of metalworking fluid, reviewing published outbreaks and clinical cases. ...
01:26
OtoRhinoLaryngology - Head and Neck Surgery
Allergy immunotherapy (AIT) is acknowledged to produce beneficial mid- and long-term clinical and immunologic effects and increased quality of life in patients with allergic respiratory diseases (such as aller…http://ift.tt/2aknD2z
01:15
Thyroid Disorders by Alexandros G.Sfakianakis
Publication date: June 2016Source:Cancer Genetics, Volume 209, Issue 6 Author(s): Caitlin Evers, Dzifa Y. Duose, Meenakshi Mehrotra, Tao Hai, Michal R. Houston, Peter C. Hu, Rajyalakshmi Luthra, Steven I. Sherman, Gilbert J. Cote from thyroid via a.lsfakia on Inoreader http://ift.tt/2ag4my9 via IFTTT
01:15
Thyroid Disorders by Alexandros G.Sfakianakis
Publication date: June 2016Source:Cancer Genetics, Volume 209, Issue 6 Author(s): Josh Haimes, Laura Johnson, James Covino, Namitha Manoj, Marc Bessette, Elina Baravik, Abel Licon, Ryan D. Walters, Laura M. Griffin, Brady P. Culver, Joshua A. Stahl, Brian A. Kudlow from thyroid via a.lsfakia on Inoreader...
00:56
Melanoma by Alexandros G. Sfakianakis
Publication date: June 2016Source:Cancer Genetics, Volume 209, Issue 6 Author(s): Alka Chaubey, Ashis Mondal, WonSok Lee, Amyn Rojiani, Barbara DuPont, Ravindra Kolhe http://ift.tt/2akqdFU
00:11
Thyroid Disorders by Alexandros G.Sfakianakis
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
00:11
Thyroid Disorders by Alexandros G.Sfakianakis
Publication date: August 2016Source:Cancer Epidemiology, Volume 43 Author(s): Susanna D. Mitro, Laura S. Rozek, Patravoot Vatanasapt, Krittika Suwanrungruang, Imjai Chitapanarux, Songpol Srisukho, Hutcha Sriplung, Rafael Meza BackgroundIodine deficiency may play a role in thyroid cancer carcinogenesis....
Fri Jul 29, 2016 23:57
Melanoma by Alexandros G. Sfakianakis
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Fri Jul 29, 2016 23:57
Melanoma by Alexandros G. Sfakianakis
by Noha Abdel-Wahab, Mohsin Shah, Maria E. Suarez-Almazor Background Three checkpoint inhibitor drugs have been approved by the US Food and Drug Administration for use in specific types of cancers. While the results are promising, severe immunotherapy-related adverse events (irAEs) have been reported....
Fri Jul 29, 2016 23:55
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Objective The aim of this study was to establish global survival rates and potential prognostic factors for mucoepidermoid carcinoma (MC) of the salivary glands in patients diagnosed at the Dr. Eduardo Cáceres Graziani National...
Fri Jul 29, 2016 23:25
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Ocular or eye pain is a frequent complaint encountered not only by eye care providers but neurologists. Isolated eye pain is non-specific and non-localizing; therefore, it poses significant differential diagnostic problems. A wide range of neurologic and ophthalmic disorders...
Fri Jul 29, 2016 23:25
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Migraine can impact every aspect of a person’s functioning. Psychological comorbidities, cognitive constructs, and behavioral responses to pain greatly impact the perception of migraine pain, treatment efficacy and outcome, and overall quality of life and functioning. Current...
Fri Jul 29, 2016 23:25
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Traumatic spinal cord injury (SCI) is a devastating neurological condition. Treatment of SCI-related pain is challenging for the treating physician, as normal neural pathways are disrupted. Patients with SCI consistently rate pain as one of the most difficult problems associated...
Fri Jul 29, 2016 23:12
Thyroid Disorders by Alexandros G.Sfakianakis
Abstract Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired...
Fri Jul 29, 2016 22:29
Melanoma by Alexandros G. Sfakianakis
Abstract Background Coffee contains biologically-active substances that suppress carcinogenesis in vivo, and coffee consumption has been associated with a lower risk of malignant melanoma. We studied the impact of total coffee consumption and of different brewing methods on the incidence of malignant...
Fri Jul 29, 2016 22:25
OtoRhinoLaryngology - Head and Neck Surgery
Abstract Purpose of Review This review summarises the clinical knowledge of hypersensitivity pneumonitis in workers exposed to aerosols of metalworking fluid, reviewing published outbreaks and clinical cases. ...
Fri Jul 29, 2016 22:14
Melanoma by Alexandros G. Sfakianakis
Abstract Recent evidence suggests that dimethylfumarate (DMF), known as a highly potent anti-psoriatic agent, might have anti-tumorigenic properties in melanoma. It has recently been demonstrated that DMF inhibits melanoma proliferation by apoptosis and cell cycle inhibition and therefore inhibits melanoma...
Fri Jul 29, 2016 21:59
Melanoma by Alexandros G. Sfakianakis
Does the association of low vitamin D levels and poor outcomes in melanoma patients point to supplementation as a potential intervention for melanoma?Medscape Oncology http://ift.tt/2aCpDps
Fri Jul 29, 2016 20:34
Audiology by Alexandros G. Sfakianakis
We have recently talked about making soundscapes from photographs and a group of professional recording artists joining forces to document the exquisite sounds of nature. The real world, no doubt, is much more sonically diverse and full. Is there a way to capture the characteristic sounds of the world...
Fri Jul 29, 2016 19:55
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: October 2016Source:Oral Oncology, Volume 61 Author(s): Douglas Adkins, Jessica Ley, Loren Michel, Tanya M. Wildes, Wade Thorstad, Hiram A. Gay, Mackenzie Daly, Jason Rich, Randal Paniello, Ravindra Uppaluri, Ryan Jackson, Kathryn Trinkaus, Brian NussenbaumObjectivesWe...
Fri Jul 29, 2016 19:55
OtoRhinoLaryngology - Head and Neck Surgery
Abstract BackgroundHouse dust mite (HDM) is the major indoor allergen for allergic diseases such as allergic rhinitis (AR) and asthma. Although sublingual immunotherapy (SLIT) is a curative treatment for HDM-induced AR, data from large-scale studies are limited. We evaluated the efficacy and safety...
Fri Jul 29, 2016 18:53
OtoRhinoLaryngology - Head and Neck Surgery
Abstract There is increasing interest in using data from oral food challenges (OFC) performed under medical supervision to assist in allergy risk management, both in industry (allergen risk management) (1) and in the clinical management of the allergic individual (2). Data relating to the minimum eliciting...
Fri Jul 29, 2016 18:48
OtoRhinoLaryngology by Alexandros G.Sfakianakis
We have recently talked about making soundscapes from photographs and a group of professional recording artists joining forces to document the exquisite sounds of nature. The real world, no doubt, is much more sonically diverse and full. Is there a way to capture the characteristic sounds of the...
Fri Jul 29, 2016 17:53
OtoRhinoLaryngology - Head and Neck Surgery
Abstract BackgroundAtopic dermatitis (AD) is a common skin disorder. Its diagnosis relies on clinical judgment. Mild and untypical manifestations may cause diagnostic difficulties. Biomarkers for the differential diagnostic work up of AD are needed. ObjectiveTo test if the results of skin provocation...
Fri Jul 29, 2016 17:53
OtoRhinoLaryngology - Head and Neck Surgery
Induction chemotherapy followed by radiation therapy (RT) is an organ-sparing treatment approach for selected sub-sites of locally advanced head and neck squamous cell carcinoma (HNSCC) [1]. Induction regimens originally included cisplatin and 5-fluorouracil (PF) [2]. However, more recent phase III trials...
Fri Jul 29, 2016 17:48
OtoRhinoLaryngology by Alexandros G.Sfakianakis
A precedence effect model is described that can use a binaural signal to robustly localize a sound source in the presence of multiple reflections for the frontal horizontal plane. The model also estimates a room impulse response from a running binaural signal and determines the spatial locations and...
Fri Jul 29, 2016 17:39
Audiology by Alexandros G. Sfakianakis
A precedence effect model is described that can use a binaural signal to robustly localize a sound source in the presence of multiple reflections for the frontal horizontal plane. The model also estimates a room impulse response from a running binaural signal and determines the spatial locations and...
Fri Jul 29, 2016 17:39
Audiology by Alexandros G. Sfakianakis
Publication date: Available online 29 July 2016Source:Gait & PostureAuthor(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie BusseyPostural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means of...
Fri Jul 29, 2016 17:39
Audiology by Alexandros G. Sfakianakis
Publication date: Available online 29 July 2016Source:Gait & PostureAuthor(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie BusseyPostural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means of...
Fri Jul 29, 2016 17:39
Audiology by Alexandros G. Sfakianakis
Publication date: Available online 29 July 2016Source:Gait & PostureAuthor(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie BusseyPostural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means of...
Fri Jul 29, 2016 17:26
Melanoma by Alexandros G. Sfakianakis
We examined liver specimens from 15 patients with uveal melanoma (UM) who had succumbed to their disseminated disease. We found two distinct growth patterns of UM metastasis: infiltrative (n=12) and nodular (n=3). In the infiltrative pattern, individual UM cells with a CD133+ cancer stem cell-like phenotype...
Fri Jul 29, 2016 17:23
OtoRhinoLaryngology - Head and Neck Surgery
A precedence effect model is described that can use a binaural signal to robustly localize a sound source in the presence of multiple reflections for the frontal horizontal plane. The model also estimates a room impulse response from a running binaural signal and determines the spatial locations and...
Fri Jul 29, 2016 17:23
OtoRhinoLaryngology - Head and Neck Surgery
Purpose of review: Scombroid poisoning is a frequent cause of admission in emergency department. In everyday clinical practice, it can be difficult to discriminate between scombroid syndrome and fish allergy. The aim of this review is to provide the clinician some instruments to make a correct differential...
Fri Jul 29, 2016 17:23
OtoRhinoLaryngology - Head and Neck Surgery
Paramedian forehead flap represents a workhorse in facial soft tissue reconstruction but always requires a second step in order to interrupt the skin bridge. Direct visualization and dissection of vascular pedicle may avoid this drawback.http://ift.tt/2a9up8q
Fri Jul 29, 2016 17:23
OtoRhinoLaryngology - Head and Neck Surgery
It is essential to have a reliable assessment method in order to compare the results of cleft lip and palate surgery. In this study the computer-based program SymNose, a method for quantitative assessment of the nose and lip, will be assessed on usability and reliability.http://ift.tt/2alTBMg
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: October 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 89 Author(s): Michael T. Yim, Huy D. Tran, Binoy M. ChandyObjectives/HypothesisTo determine the epidemiology of incidental thyroglossal duct cysts (TGDC) discovered on imaging studies obtained...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: October 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 89 Author(s): F. Mozzanica, R. Salvadorini, E. Sai, R. Pozzoli, P. Maruzzi, L. Scarponi, M.R. Barillari, E. Spada, F. Ambrogi, A. SchindlerObjectivesEvaluation of the reliability...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: October 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 89 Author(s): Vasileios Gkiousias, Christopher Collett Butler, Victoria Shepherd, James Michael Kilgour, Cherry-Ann Waldron, Emma Thomas-Jones, Nick FrancisObjectivesOtitis media with...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: Available online 28 July 2016Source:International Journal of Oral and Maxillofacial Surgery Author(s): H. Rushinek, R. Tabib, Y. Fleissig, M. Klein, S. TshoriThe aims of the study were to evaluate the diagnostic accuracy and utility of the mean region of interest (ROI)...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Rick M. Maizels, Henry J. McSorleyHelminth parasite infections are associated with a battery of immunomodulatory mechanisms, which impact all facets of the host immune response to ensure...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Sara Ciullini Mannurita, Marina Vignoli, Gloria Colarusso, Fabio Tucci, Marinella Veltroni, Stefano Frenos, Veronica Tintori, Maurizio Aricò, Venetia Bigley, Matthew Collin,...
Fri Jul 29, 2016 16:52
OtoRhinoLaryngology - Head and Neck Surgery
Publication date: Available online 29 July 2016Source:Journal of Allergy and Clinical Immunology Author(s): Yuko Kawakami, Tomoaki Ando, Jong-Rok Lee, Gisen Kim, Yu Kawakami, Tae Nakasaki, Manando Nakasaki, Kenji Matsumoto, Youn Soo Choi, Toshiaki KawakamiBackgroundPatients with...
Fri Jul 29, 2016 16:47
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Publication date: Available online 29 July 2016Source:Gait & Posture Author(s): Daniela Aldabe, Pedduzzi Marcelo Castro, Stephan Milosavljevic, Dawn Melanie Bussey Postural adjustment evaluations during single leg lift requires the initiation of heel lift (T1) identification. T1 measured by means...
Fri Jul 29, 2016 16:21
OtoRhinoLaryngology - Head and Neck Surgery
First described by Jaffe in 1953, central giant cell lesions are defined by the World Health Organisation as “a localized benign but sometimes aggressive osteolytic proliferation consisting of fibrous tissue with haemorrhage and haemosiderin deposits, presence of osteoclast-like giant cells and reactive...
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