Staphylococcus epidermidis (S. epidermidis) is an opportunistic pathogen with low pathogenicity and a cause of the repeated outbreak of bovine mastitis in veterinary clinical settings. In this report, a biofilm model of S. epidermidis was generated and the minimal inhibitory concentration (MIC) and sub-MIC (SMIC) on bacterial cultures were assessed for the following agents: total alkaloids of Sophora alopecuroides (TASA), ciprofloxacin (CIP), and erythromycin (ERY). The formation and characteristic parameters of biofilm were analyzed in terms of XTT assay, silver staining, and confocal laser scanning microscope (CLSM). Results showed that a sub-MIC of TASA could inhibit 50% biofilm of bacterial activity, while 250-fold MIC of CIP and ERY MICs only inhibited 50% and 47% of biofilm formation, respectively. All three agents could inhibit the biofilm formation at an early stage, but TASA showed a better inhibitory effect on the late stage of biofilm thickening. A morphological analysis using CLSM further confirmed the destruction of biofilm by these agents. These results thus suggest that TASA has an inhibitory effect on biofilm formation of clinic S. epidermidis, which may be a potential agent warranted for further study on the treatment prevention of infection related to S. epidermidis in veterinary clinic.
from #Medicine via ola Kala on Inoreader http://ift.tt/24YMRWE
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Ιουνίου
(946)
-
▼
Ιουν 19
(24)
- Micromachines, Vol. 7, Pages 104: A Robot-Assisted...
- Inorganics, Vol. 4, Pages 19: Monoanionic Tin Olig...
- Humanities, Vol. 5, Pages 47: “I Felt Like My Life...
- Micromachines, Vol. 7, Pages 105: Fabrication of D...
- Entropy, Vol. 18, Pages 229: Investigating Aging-R...
- Energies, Vol. 9, Pages 449: Variability Character...
- IJGI, Vol. 5, Pages 99: Evaluation of Deterministi...
- Atoms, Vol. 4, Pages 17: Series of Broad Resonance...
- Applied Sciences, Vol. 6, Pages 179: Output Proper...
- MCA, Vol. 21, Pages 25: Fixed Order Controller for...
- Modeling heterogeneity in the pluripotent state: A...
- SYMPOSIUM: First international conference on myositis
- Diagnosis and classification of idiopathic inflamm...
- New ways to subclassify patients with myositis
- Issue Information - Editorial Board
- Effect of Collaborative Recommender System Paramet...
- Key Molecular Mechanisms of Chaiqinchengqi Decocti...
- Immunopathological Features of Canine Myocarditis ...
- Herbal Medicines for Treating Metabolic Syndrome: ...
- The Effect of Glutamate Receptor Agonists on Mouse...
- Effects of Total Alkaloids of Sophora alopecuroide...
- High Glucose-Induced PC12 Cell Death by Increasing...
- Isolation and Identification of the Antimicrobial ...
- Assessment of Tree Leaves Flakes Mixed with Crude ...
-
▼
Ιουν 19
(24)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Κυριακή 19 Ιουνίου 2016
Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.