The major active constituents from Amaryllidaceae family were reported to be Amaryllidaceae alkaloids (AAs), which exhibited a wide spectrum of biological activities, such as anti-tumor, anti-viral, and acetyl-cholinesterase-inhibitory activities. In order to better understand their potential as a source of bioactive AAs and the phytochemical variations among three different species of Lycoris herbs, the HPLC fingerprint profiles of Lycoris aurea (L. aurea), L. radiata, and L. guangxiensis were firstly determined and compared using LC-UV and LC-MS/MS. As a result, 39 peaks were resolved and identified as AAs, of which nine peaks were found in common for all these three species, while the other 30 peaks could be revealed as characteristic AAs for L. aurea, L. radiata and L. guangxiensis, respectively. Thus, these AAs can be used as chemical markers for the identification and quality control of these plant species. To further reveal correlations between chemical components and their pharmaceutical activities of these species at the molecular level, the bioactivities of the total AAs from the three plant species were also tested against HepG2 cells with the inhibitory rate at 78.02%, 84.91% and 66.81% for L. aurea, L. radiata and L. guangxiensis, respectively. This study firstly revealed that the three species under investigation were different not only in the types of AAs, but also in their contents, and both contributed to their pharmacological distinctions. To the best of our knowledge, the current research provides the most detailed phytochemical profiles of AAs in these species, and offers valuable information for future valuation and exploitation of these medicinal plants.
from #Medicine via ola Kala on Inoreader http://ift.tt/1XPgED0
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
2015
(2119)
-
▼
Δεκεμβρίου
(940)
-
▼
Δεκ 07
(50)
- Smart modification of the single conical nanochann...
- Bioluminescent bioreporter pad biosensor for monit...
- Exploring the Link between the Components of Metab...
- IJMS, Vol. 16, Pages 29148-29160: Primary Phenomen...
- Photonics, Vol. 2, Pages 1152-1163: InP-Based Wave...
- IJMS, Vol. 16, Pages 29120-29133: Phenolic Phytoal...
- IJMS, Vol. 16, Pages 29161-29178: Antioxidant and ...
- IJMS, Vol. 16, Pages 29134-29147: Allyl Isothiocya...
- IJMS, Vol. 16, Pages 29103-29119: Tumor-Associated...
- IJMS, Vol. 16, Pages 29179-29206: Bioinformatics M...
- Risks, Vol. 3, Pages 573-598: Information-Based Tr...
- Molecules, Vol. 20, Pages 21854-21869: Comparative...
- Molecules, Vol. 20, Pages 21840-21853: Alkylation ...
- Pharmaceutics, Vol. 7, Pages 542-553: Genomic Disc...
- Symmetry, Vol. 7, Pages 2195-2205: Estrada Index o...
- Sensors, Vol. 15, Pages 30810-30826: Calibration T...
- Technologies, Vol. 3, Pages 285-301: Effect of Ext...
- Sensors, Vol. 15, Pages 30827-30838: Maximum-Likel...
- Buildings, Vol. 5, Pages 1346-1360: The Use of Sou...
- Micromachines, Vol. 6, Pages 1914-1922: High Speed...
- Micromachines, Vol. 6, Pages 1923-1934: A Simple a...
- Gels, Vol. 1, Pages 235-255: Precise Control over ...
- Laws, Vol. 4, Pages 755-770: Embryonic Human Life ...
- Editorial Board/Aims and Scope
- A Brazilian report using serological and molecular...
- Emotion socialization practices in Italian and Hon...
- The Role of Toll-Like Receptors and Myeloid Differ...
- Protective effects of exercise in metabolic disord...
- Identification of the specific epigenetic alterati...
- “Cystic fibrotics could survive cholera, choleraic...
- A suggestion about the cause of inflammation in ac...
- A hypothesis about how to achieve anticoagulation ...
- Title page/Editorial Board
- Possible scenarios of the influence of low-dose io...
- Adiponutrin (PNPLA3) in liver fibrogenesis: Is una...
- Effect of protein arginine methyltransferase-1 inh...
- The transcription, translation, transport-trail an...
- Size of quadriceps femoris may contribute to thyro...
- Fatty acyl composition of lysophosphatidylcholine ...
- Possible role of granulysin in pathogenesis of ost...
- Baicalin may have a therapeutic effect in attentio...
- Myalgic encephalomyelitis, chronic fatigue syndrom...
- Mechanism of failure of the Cabrol procedure: A co...
- Review of Amyotrophic Lateral Sclerosis, Parkinson...
- Non-pharmacological treatment for neuropathic pain...
- On the origins of autism: The Quantitative Thresho...
- PET Radioligands Reveal the Basis of Dementia in P...
- IJERPH, Vol. 12, Pages 15516-15530: Adult Lifespan...
- IJERPH, Vol. 12, Pages 15531-15539: Association of...
- IJERPH, Vol. 12, Pages 15498-15515: A Systematic R...
-
▼
Δεκ 07
(50)
-
▼
Δεκεμβρίου
(940)
Αναζήτηση αυτού του ιστολογίου
Δευτέρα 7 Δεκεμβρίου 2015
Molecules, Vol. 20, Pages 21854-21869: Comparative Analysis of Amaryllidaceae Alkaloids from Three Lycoris Species
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.