Protein by-products from the extraction of lecithin from egg yolk can be converted into value-added products, such as bioactive hydrolysates and peptides that have potential health enhancing antioxidant, and antihypertensive properties. In this study, the antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of peptides isolated and purified from egg yolk protein were investigated. Defatted egg yolk was hydrolyzed using pepsin and pancreatin and sequentially fractionated by ultrafiltration, followed by gel filtration to produce egg yolk gel filtration fractions (EYGF). Of these, two fractions, EYGF-23 and EYGF-33, effectively inhibited the peroxides and thiobarbituric acid reactive substance (TBARS) in an oxidizing linoleic acid model system. The antioxidant mechanism involved superoxide anion and hydroxyl radicals scavenging and ferrous chelation. The presence of hydrophobic amino acids such as tyrosine (Y) and tryptophan (W), in sequences identified by LC-MS as WYGPD (EYGF-23) and KLSDW (EYGF-33), contributed to the antioxidant activity and were not significantly different from the synthetic BHA antioxidant. A third fraction (EYGF-56) was also purified from egg yolk protein by gel filtration and exhibited high ACE inhibitory activity (69%) and IC50 value (3.35 mg/mL). The SDNRNQGY peptide (10 mg/mL) had ACE inhibitory activity, which was not significantly different from that of the positive control captopril (0.5 mg/mL). In addition, YPSPV in (EYGF-33) (10 mg/mL) had higher ACE inhibitory activity compared with captopril. These findings indicated a substantial potential for producing valuable peptides with antioxidant and ACE inhibitory activity from egg yolk.
from #Medicine via ola Kala on Inoreader http://ift.tt/1XPgGuy
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
2015
(2119)
-
▼
Δεκεμβρίου
(940)
-
▼
Δεκ 07
(50)
- Smart modification of the single conical nanochann...
- Bioluminescent bioreporter pad biosensor for monit...
- Exploring the Link between the Components of Metab...
- IJMS, Vol. 16, Pages 29148-29160: Primary Phenomen...
- Photonics, Vol. 2, Pages 1152-1163: InP-Based Wave...
- IJMS, Vol. 16, Pages 29120-29133: Phenolic Phytoal...
- IJMS, Vol. 16, Pages 29161-29178: Antioxidant and ...
- IJMS, Vol. 16, Pages 29134-29147: Allyl Isothiocya...
- IJMS, Vol. 16, Pages 29103-29119: Tumor-Associated...
- IJMS, Vol. 16, Pages 29179-29206: Bioinformatics M...
- Risks, Vol. 3, Pages 573-598: Information-Based Tr...
- Molecules, Vol. 20, Pages 21854-21869: Comparative...
- Molecules, Vol. 20, Pages 21840-21853: Alkylation ...
- Pharmaceutics, Vol. 7, Pages 542-553: Genomic Disc...
- Symmetry, Vol. 7, Pages 2195-2205: Estrada Index o...
- Sensors, Vol. 15, Pages 30810-30826: Calibration T...
- Technologies, Vol. 3, Pages 285-301: Effect of Ext...
- Sensors, Vol. 15, Pages 30827-30838: Maximum-Likel...
- Buildings, Vol. 5, Pages 1346-1360: The Use of Sou...
- Micromachines, Vol. 6, Pages 1914-1922: High Speed...
- Micromachines, Vol. 6, Pages 1923-1934: A Simple a...
- Gels, Vol. 1, Pages 235-255: Precise Control over ...
- Laws, Vol. 4, Pages 755-770: Embryonic Human Life ...
- Editorial Board/Aims and Scope
- A Brazilian report using serological and molecular...
- Emotion socialization practices in Italian and Hon...
- The Role of Toll-Like Receptors and Myeloid Differ...
- Protective effects of exercise in metabolic disord...
- Identification of the specific epigenetic alterati...
- “Cystic fibrotics could survive cholera, choleraic...
- A suggestion about the cause of inflammation in ac...
- A hypothesis about how to achieve anticoagulation ...
- Title page/Editorial Board
- Possible scenarios of the influence of low-dose io...
- Adiponutrin (PNPLA3) in liver fibrogenesis: Is una...
- Effect of protein arginine methyltransferase-1 inh...
- The transcription, translation, transport-trail an...
- Size of quadriceps femoris may contribute to thyro...
- Fatty acyl composition of lysophosphatidylcholine ...
- Possible role of granulysin in pathogenesis of ost...
- Baicalin may have a therapeutic effect in attentio...
- Myalgic encephalomyelitis, chronic fatigue syndrom...
- Mechanism of failure of the Cabrol procedure: A co...
- Review of Amyotrophic Lateral Sclerosis, Parkinson...
- Non-pharmacological treatment for neuropathic pain...
- On the origins of autism: The Quantitative Thresho...
- PET Radioligands Reveal the Basis of Dementia in P...
- IJERPH, Vol. 12, Pages 15516-15530: Adult Lifespan...
- IJERPH, Vol. 12, Pages 15531-15539: Association of...
- IJERPH, Vol. 12, Pages 15498-15515: A Systematic R...
-
▼
Δεκ 07
(50)
-
▼
Δεκεμβρίου
(940)
Αναζήτηση αυτού του ιστολογίου
Δευτέρα 7 Δεκεμβρίου 2015
IJMS, Vol. 16, Pages 29161-29178: Antioxidant and ACE Inhibitory Bioactive Peptides Purified from Egg Yolk Proteins
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.