Pulmonary metastasis of mesonephric‐like adenocarcinoma arising from the uterine body: a striking mimicry of follicular thyroid carcinoma

Abstract

Mesonephric adenocarcinoma (MNAC) is a rare neoplasm that presumably develops from the mesonephric remnants, occurring mostly in the uterine cervix and, to a lesser extent, the vagina, uterine body, ovary, and para‐adnexal soft tissues. Histologically, MNAC exhibits a variety of architectural growth patterns, even within the same tumour, including tubular, glandular, papillary, solid, and retiform, and therefore may be confused with more common carcinomas of Müllerian origin. Moreover, the tubules with luminal eosinophilic secretions, a common characteristic of MNACs, may result in consideration of thyroidal carcinoma when tumours spread beyond the pelvis. Immunohistochemistry can identify the mesonephric nature of the tumour, that is, negative for hormone receptors and positive for CD10, calretinin, and GATA binding protein 3 (GATA3) in variable degrees

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