African trypanosomes cause human and veterinary disease throughout sub‐Saharan Africa. The parasite cycles between the insect vector, tsetse flies, and the mammalian host, where they live free in the blood and extracellular spaces. Trypanosomes use a remarkable process of antigenic variation to survive in the face of the host adaptive immune response. Further details can be found in article number 1800181 by James D. Bangs.
Photo Credits:
Trypanosome: Peter Bush, School of Dental Medicine, University at Buffalo African
Cattle: Keith Matthews, Institute of Immunology and Infection Research, University of Edinburgh
Postprandial Tsetse: Geoffrey Attardo, Department of Entomology and Nematology, University of California Davis.
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