Local Relapse after Breast Conserving Therapy vs. Mastectomy for Extensive Pure Ductal Carcinoma In-Situ ≥4 cm

This study evaluates population-based outcomes for patients with extensive (≥4 centimeters) pure ductal carcinoma in-situ (DCIS). Local recurrence was 2% with mastectomy, 8% with breast conserving surgery (BCS) and radiotherapy and 16% with BCS alone. Mastectomy remains a standard local treatment for extensive DCIS, while BCS and radiotherapy may be reasonably considered in selected patients with a careful discussion of the benefits and side effects.

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