Dosimetric benefits of mid-position compared with internal target volume strategy for esophageal cancer radiation therapy

Two strategies to account for respiration-induced target motion using 4D-CT in treatment planning of esophageal cancer patients (i.e., mid-position and internal target volume) were compared in 15 patients. Deformable image registration-based 4D-dose accumulation indicated adequate target coverage and a reduction of approximately 10% in the dose to the lungs, heart, and liver for the mid-position strategy. Our results suggest clinically relevant dosimetric benefits for the mid-position strategy and its feasibility of clinical implementation.

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