Cost and Cost-Effectiveness of Image Guided Partial Breast Irradiation in Comparison to Hypofractionated Whole Breast Irradiation

Based on micro-costing analysis, accelerated partial breast irradiation (APBI) delivered with IMRT in 5 fractions was less costly to deliver than hypofractionated whole breast irradiation (HWBI) with or without boost and additionally had higher utility outcomes. When utilizing reimbursement, IMRT APBI was less costly than HWBI with or without boost, dominating the technique; however, when billed as SBRT it was not cost-effective.

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