Guardians at the Gate: Pediatricians, Colic and Clinical Research

Descriptions of infant colic extend back to the time of Galen when reports about calming a fussy baby emerged. Academic reports describing colic and hypothesizing etiology date back to 1954, when Illingsworth and Wessel published 2 independent reports describing colic and possible causes as understood at the time.1,2 Infant colic continues to be a frustrating syndrome for parents and pediatricians despite numerous studies with several hypotheses for etiology and treatments. Treatment has included the use of opiates applied to the mother's nipples in the time of Galen to the use of prebiotics today.

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