(OA12) Pulsed Reduced Dose Rate Re-Irradiation (PRDR) Using Modulated ARC (MARC) IMRT for Recurrent Gliomas: Initial Clinical Outcomes of a Novel Technique

Limited salvage options exist for patients with recurrent malignant brain tumors after standard treatment. Pulsed reduced dose rate re-irradiation (PRDR) is a biologically-unique strategy that lowers the effective dose rate, potentially decreasing toxicity by allowing for greater sublethal damage repair in normal tissue. It has been shown to be safe and effective in patients with recurrent gliomas using a 3DRT technique. We developed a novel technique using PRDR with modulated arc (mARC) IMRT delivery to further reduce the amount of normal tissue exposed.

https://ift.tt/2rgsA3W