TPF Induction Chemotherapy Prior to Chemoradiation for Locally Advanced Nasopharyngeal Carcinoma

Platinum-based chemoradiation (CRT) with or without adjuvant chemotherapy is considered standard treatment for locally advanced nasopharyngeal carcinoma (LA NPC). Recently, a large randomized trial reported overall survival benefit with TPF induction chemotherapy (IC) prior to CRT compared to CRT alone. We have used TPF IC prior to CRT selectively in patients (pts) with symptomatic LA NPC and report our outcomes with this approach.

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