What Is the Utility of Coronary Computed Tomography Angiography Compared With Standard of Care for the Evaluation of Acute Chest Pain?

The search strategy identified 648 articles, of which 10 trials (6,285 total participants) met the inclusion criteria. The studies were published between 2007 and 2016, and none were determined to be at high risk of bias. Six studies were performed in the ED and 4 studies were performed in the inpatient setting. The mean age ranged from 50 to 60 years, and the percentage of female patients ranged from 42% to 63%. Eight studies excluded patients with known coronary artery disease. Standard of care included myocardial perfusion imaging in 8 studies, stress ECG in 5 studies, and stress echocardiogram in 2 studies.

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