Incidental iatrogenic form of collagenized organizing pneumonia

We read with interest the study from Dr Yousem [1] describing a cicatricial form of cryptogenic organizing pneumonia (COP) in 12 patients presenting with bilateral, nodular or reticulonodular disease. All but one were symptomatic, and none had extra-thoracic diseases. Histologically, the lesions were characterized by collagenization of the fibromyxoid polyps of OP pattern, while the underlying lung architecture was preserved. Most of the patients (10 out of 12) had a response to steroids. (See Fig.

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