Understanding the molecular basis for the development of HIV Env-specific bnAbs is key for vaccine design. Andrabi et al. find that CAP256 V2 apex lineage Abs affinity mature with sialic acid containing complex-type glycans on HIV envelope trimer. This glycan recognition enables the development into bnAbs by resisting virus escape.
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Τρίτη 12 Σεπτεμβρίου 2017
Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
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