95 Safety and Efficacy of Dantrolene Sodium (250 mg/5 mL) in Patients With Exertional Heat Stroke

Exertional heat stroke (EHS) is a rare, life-threatening condition that may affect anyone performing intense physical activity, especially in a hot environment. Morbidity and mortality persist despite aggressive cooling. EHS is a leading cause of death in young athletes and non-combat-related deaths in the military. EHS affects outdoor workers, firefighters, and people performing intense physical activities in hot weather. Severe hyperthermia and CNS dysfunction are hallmark features; rhabdomyolysis, renal failure, liver damage, and coagulation abnormalities are common and as many as 1/3 of survivors have long-term neurologic deficits despite the use of aggressive cooling.

http://ift.tt/2wCIzd4