High content imaging (HCI) is a multiplexed cell staining assay developed for better understanding of complex biological functions and mechanisms of drug action, and it has become an important tool for toxicity and efficacy screening of drug candidates. Conventional HCI assays have been carried out on two-dimensional (2D) cell monolayer cultures, which in turn limit predictability of drug toxicity/efficacy in vivo; thus, there has been an urgent need to perform HCI assays on three-dimensional (3D) cell cultures. Although 3D cell cultures better mimic in vivo microenvironments of human tissues and provide an in-depth understanding of the morphological and functional features of tissues, they are also limited by having relatively low throughput and thus are not amenable to high-throughput screening (HTS). One attempt of making 3D cell culture amenable for HTS is to utilize miniaturized cell culture platforms. This review aims to highlight miniaturized 3D cell culture platforms compatible with current HCI technology.
from #Medicine via ola Kala on Inoreader http://ift.tt/1P1ZufC
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
2015
(2119)
-
▼
Δεκεμβρίου
(940)
-
▼
Δεκ 14
(64)
- Review of Surface Enhanced Raman Scattering Applic...
- Simultaneous detection of single-nucleotide polymo...
- In vitro antiviral activity against rotavirus and ...
- Characterization of mannanase from Bacillus circul...
- Predicting the risk of sudden cardiac death
- TRPM7 kinase activity regulates murine mast cell d...
- Predicting drug-induced QT prolongation and torsad...
- Sex differences in vascular endothelial function a...
- Supersensitive and selective detection of picric a...
- Mass spectrometry of modified RNAs: recent develop...
- Probing DNA-stabilized fluorescent silver nanoclus...
- Emulsion technologies for multicellular tumour sph...
- Tualang Honey Protects against BPA-Induced Morphol...
- Breast Cancer Cell Colonization of the Human Bone ...
- In Vivo Autofluorescence Imaging of Tumor Heteroge...
- Combining Optical Reporter Proteins with Different...
- Polyploidy Formation in Doxorubicin-Treated Cancer...
- Table of Contents
- Genetic Variations in Inflammatory Response Genes ...
- Can Healthcare Assistant Training (CHAT) improve t...
- IJMS, Vol. 16, Pages 29797-29814: The Mechanisms o...
- IJMS, Vol. 16, Pages 29787-29796: Identification o...
- Genotyping HLA-B*5801 for Allopurinol-Induced Seve...
- Highly CO2 sensitive extruded fluorescent plastic ...
- IJERPH, Vol. 12, Pages 15860-15874: Autonomic Nerv...
- Catalysts, Vol. 5, Pages 2134-2146: Facile Synthes...
- JDB, Vol. 3, Pages 129-157: Cell Fate Decision Mak...
- Fibers, Vol. 3, Pages 539-559: The Influence of CF...
- Agriculture, Vol. 5, Pages 1277-1288: Selenium Bio...
- Cancers, Vol. 7, Pages 2459-2465: Acute Myeloid Le...
- Biomolecules, Vol. 5, Pages 3448-3466: On the Role...
- Biosensors, Vol. 5, Pages 768-790: High Content Im...
- Information, Vol. 6, Pages 866-879: Codeword Struc...
- JSAN, Vol. 4, Pages 378-409: The Efficacy of Epide...
- Metals, Vol. 5, Pages 2383-2392: A Simple Up-Scala...
- Marine Drugs, Vol. 13, Pages 7390-7402: Algal Toxi...
- Membranes, Vol. 5, Pages 915-923: NMR Studies of S...
- Resources, Vol. 4, Pages 939-957: A Standard Chara...
- IJMS, Vol. 16, Pages 29797-29814: The Mechanisms o...
- Glucose transporters 1, 3, 6, and 10 are expressed...
- Enteral feeding therapy for maintaining remission ...
- Modeling the ecologic niche of plague in sylvan an...
- Evaluating pharmacological models of high and low ...
- Emerging semantics to link phenotype and environment
- Analysis of synonymous codon usage patterns in six...
- Specific labeling: An effective tool to explore th...
- Sensors, Vol. 15, Pages 31464-31481: Probabilistic...
- Sensors, Vol. 15, Pages 31482-31524: Robust 3D Pos...
- Sensors, Vol. 15, Pages 31442-31452: Multiple-Para...
- Viruses, Vol. 7, Pages 6604-6612: Recent Advances ...
- Uncommon Trimethoxylated Flavonol Obtained from Ru...
- The Preventive Effect on Ethanol-Induced Gastric L...
- Effectiveness of legislative changes obligating no...
- Extended follow-up of lung cancer and non-malignan...
- Pesticide use and risk of end-stage renal disease ...
- Ambient air pollution and risk of tuberculosis: a ...
- World Trade Center-related physical and mental hea...
- Agricultural pesticide exposure and chronic kidney...
- Incidence and mortality risks for circulatory dise...
- Heavy lifting at work and risk of retinal detachme...
- The joint effect of asbestos exposure, tobacco smo...
- Effectiveness of workplace interventions in the pr...
- Exposure to loud noise, bilateral high-frequency h...
- Author response: Extended follow-up of lung cancer...
-
▼
Δεκ 14
(64)
-
▼
Δεκεμβρίου
(940)
Αναζήτηση αυτού του ιστολογίου
Δευτέρα 14 Δεκεμβρίου 2015
Biosensors, Vol. 5, Pages 768-790: High Content Imaging (HCI) on Miniaturized Three-Dimensional (3D) Cell Cultures
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.