Adoue et al. find that the histone methyltransferase SETDB1 ensures T helper cell lineage integrity not by directly controlling genes associated with T helper cell differentiation but rather by repressing a restricted set of endogenous retroviruses that have been co-opted for the regulation of immune genes.
http://bit.ly/2Dl1zT5
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Αναζήτηση αυτού του ιστολογίου
Τρίτη 5 Φεβρουαρίου 2019
The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses
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