Visual processing in migraineurs depends on the migraine cycle

Abstract

We investigated changes of afterimage‐duration in migraineurs and healthy controls (HC) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. 47 episodic (EM) and 39 chronic migraineurs (CM) (interictal) were compared to 34 HC for visual after‐image duration. Additionally, seven EM were investigated every consecutive day over 20‐32 days using the identical paradigm throughout the migraine cycle. Interictally, the after‐image duration was shorter compared to HC but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs which oscillates over the migraine cycle.

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