Early Detection of Hepatocellular Carcinoma ‐ Expanding the Utility of Circulating Tumor Markers

Abstract

The global prevalence of hepatocellular cancer (HCC) underscores the need for effective strategies that can reduce the burden and impact of this disease. The increase in the incidence and mortality from HCC in the United States and Europe further emphasize the need for early detection to identify tumors at an early stage and amenable to curative treatments Screening and surveillance for HCC in patients with cirrhosis has been shown to improve survival. Guidelines from major professional societies encourage surveillance for HCC in patients with cirrhosis, advanced fibrosis or high risk hepatitis B virus (HBV) infection.

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